克罗地亚核医学诊断程序对人群的估计集体有效剂量：2010年与2015年的比较。
Estimated collective effective dose to the population from nuclear medicine diagnostic procedures in Croatia: A comparison of 2010 and 2015.
作者信息
Kralik Ivana, Štefanić Mario, Brkić Hrvoje, Šarić Gordan, Težak Stanko, Grbac Ivanković Svjetlana, Griotto Neva, Štimac Damir, Rubin Otmar, Salha Tamer, Ivanišević Zrinka, Jurković Slaven, Faj Dario
机构信息
State Office for Radiological and Nuclear Safety, Zagreb, Croatia.
Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
出版信息
PLoS One. 2017 Jun 29;12(6):e0180057. doi: 10.1371/journal.pone.0180057. eCollection 2017.
OBJECTIVE
This study presents national surveys of patient exposure from nuclear medicine (NM) diagnostic procedures in 2010 and 2015 in the Republic of Croatia.
METHODS
The survey was performed according to the European Commission Dose DataMed (DDM) project methodology. 28 most frequent NM diagnostic procedures were identified. Data about frequencies of procedures and average administered activities of radioisotopes used in those procedures were collected. Average administered activities were converted to effective doses according to the dose conversion coefficients. Then the collective effective dose to the population and an effective dose per capita were calculated based on the number of the most frequent NM diagnostic procedures and the average effective dose per procedure.
RESULTS
In 2010, 41200 NM diagnostic procedures led to 146.7 manSv collective effective dose to the population and in 2015, 42000 NM diagnostic procedures led to 146.8 manSv collective effective dose to the population. The frequencies of NM diagnostic procedures were 9.7 and 9.8 annually per 1000 population with 34.1 μSv and 34.2 μSv effective dose per capita for 2010 and 2015, respectively. The main contributors to the annual collective dose from NM in Croatia are examinations of the bone, heart, thyroid and PET/CT tumour diagnostic. Average administered activities have not changed considerably from 2010 to 2015. Nevertheless, within the frequency of some of the procedures, significant changes were found in five-year period.
CONCLUSIONS
Frequencies, average administered activities and collective effective dose to the population from NM diagnostic procedures in Croatia are comparable to the values reported by other European surveys. Changes were found between 2010 and 2015 and we intend to perform this study periodically to identify possible trends, but also to raise awareness about the potential dose optimization.
目的
本研究展示了2010年和2015年克罗地亚共和国针对核医学（NM）诊断程序的全国患者照射情况调查。
方法
该调查按照欧盟委员会剂量数据医学（DDM）项目方法进行。确定了28种最常见的NM诊断程序。收集了这些程序的执行频率以及所用放射性同位素的平均给药活度数据。根据剂量转换系数将平均给药活度转换为有效剂量。然后根据最常见的NM诊断程序数量和每个程序的平均有效剂量，计算出人群的集体有效剂量和人均有效剂量。
结果
2010年，41200例NM诊断程序导致人群集体有效剂量为146.7人·希沃特，2015年，42000例NM诊断程序导致人群集体有效剂量为146.8人·希沃特。2010年和2015年，NM诊断程序的频率分别为每1000人口每年9.7次和9.8次，人均有效剂量分别为34.1微希沃特和34.2微希沃特。克罗地亚NM年度集体剂量的主要贡献来自骨骼、心脏、甲状腺检查以及PET/CT肿瘤诊断。从2010年到2015年，平均给药活度变化不大。然而，在某些程序的频率方面，五年内发现了显著变化。
结论
克罗地亚NM诊断程序的频率、平均给药活度和人群集体有效剂量与其他欧洲调查报道的值相当。2010年至2015年期间发现了变化，我们打算定期进行这项研究以确定可能的趋势，同时提高对潜在剂量优化的认识。
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