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栓塞治疗重度甲型血友病患儿难治性亚急性硬膜下血肿

Embolization for Refractory Subacute Subdural Hematoma in a Child with Severe Hemophilia Type A.

作者信息

Higaki Ayuho, Namba Katsunari, Watanabe Eiju, Nemoto Shigeru, Gomi Akira

机构信息

Department of Neurosurgery, Jichi Medical University, Shimotsuke, Tochigi, Japan.

Center for Endovascular Therapy, Division of Neuroendovascular Surgery, Jichi Medial University, Shimotsuke, Tochigi, Japan.

出版信息

NMC Case Rep J. 2015 Dec 5;4(1):11-14. doi: 10.2176/nmccrj.cr.2016-0041. eCollection 2017 Jan.

Abstract

Hemophilia is an X-linked hemorrhagic disease due to coagulation factor VIII or IX deficiency with approximately 5-10% incidence of central nervous system bleeding. We present an intriguing case of a refractory subacute subdural hematoma (SDH) controlled with endovascular embolization in a hemophilic patient. A 5-year-old severe hemophilic A boy presented with a life threatening left parietal subcortical hemorrhage, for which he underwent craniotomy and evacuation of the hematoma. Recurrent hemorrhage necessitated a repeat craniotomy. This was followed by three episodes of SDH development at the craniotomy site that were treated surgically, and finally controlled with embolization in the subacute period. This case presents a novel option for treating a refractory SDH in patients with coagulation disorders.

摘要

血友病是一种由于凝血因子 VIII 或 IX 缺乏引起的 X 连锁出血性疾病,中枢神经系统出血的发生率约为 5-10%。我们报告了一例血友病患者难治性亚急性硬膜下血肿(SDH)通过血管内栓塞得到控制的有趣病例。一名 5 岁的重度甲型血友病男孩出现危及生命的左侧顶叶皮质下出血,为此他接受了开颅手术和血肿清除术。反复出血需要再次开颅手术。随后在开颅手术部位发生了三次 SDH,均接受了手术治疗,最终在亚急性期通过栓塞得到控制。该病例为治疗凝血障碍患者的难治性 SDH 提供了一种新的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ef/5364900/4e4e75746ba6/nmccrj-4-011-g001.jpg

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