Fjørtoft Toril, Ustad Tordis, Follestad Turid, Kaaresen Per Ivar, Øberg Gunn Kristin
Clinics of Clinical services, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway.
Clinics of Clinical services, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway.
Early Hum Dev. 2017 Sep;112:20-24. doi: 10.1016/j.earlhumdev.2017.06.008. Epub 2017 Jun 30.
Studies of preterm and term-born infants have shown absent fidgety movements and an abnormal movement character to be related to brain lesions and unfavourable neurological outcomes.
The present study examines what effect a parent-administered early intervention program applied to preterm infants in a randomised control trial (RCT) between 34 and 36weeks gestational age has on their fidgety movements and overall movement character at three months of age.
The study was part of the RCT in an early intervention programme including preterm infants born between 2010 and 2014 at three Norwegian university hospitals.
130 preterm infants participated in the study, with 59 of them in the control group and 71 in the intervention group.
Fidgety movements and overall movement character at three months corrected age.
No difference was found between the intervention group and the control group in terms of fidgety movements or movement character. Approximately half of the infants in both groups showed an abnormal movement character.
No evidence was found in this RCT to suggest that an intervention at 34 to 37weeks gestational age has a significant effect on the fidgety movements or overall movement character of preterm infants. This is in line with the assumption that absent fidgety movements and an abnormal movement character are due to permanent brain injury and are therefore good predictors for later neurological impairments.
对早产儿和足月儿的研究表明，不安运动的缺失和异常的运动特征与脑损伤及不良神经学预后相关。
本研究探讨在一项随机对照试验（RCT）中，对孕龄34至36周的早产儿实施家长参与的早期干预项目，对其3个月大时的不安运动和整体运动特征有何影响。
该研究是一项早期干预项目RCT的一部分，该项目纳入了2010年至2014年在挪威三家大学医院出生的早产儿。
130名早产儿参与了研究，其中59名在对照组，71名在干预组。
矫正年龄3个月时的不安运动和整体运动特征。
干预组和对照组在不安运动或运动特征方面未发现差异。两组中约一半的婴儿表现出异常的运动特征。
在这项RCT中没有证据表明孕龄34至37周时的干预对早产儿的不安运动或整体运动特征有显著影响。这与以下假设一致，即不安运动的缺失和异常的运动特征是由永久性脑损伤引起的，因此是后期神经损伤的良好预测指标。
