Prabhakar Nanduri R, Peng Ying-Jie
Institute for Integrative Physiology and Center for Systems Biology of O2 Sensing, Biological Sciences Division, University of Chicago, Chicago, IL, 60637, USA.
Adv Exp Med Biol. 2017;977:3-8. doi: 10.1007/978-3-319-55231-6_1.
It is now well established that carotid bodies are sensory organs for monitoring arterial blood oxygen levels and trigger reflexes that are critical for maintaining homeostasis during hypoxemia. This review article provides a brief account of the early studies leading to the discovery of the carotid body as a sensory receptor and addresses current views of O sensing mechanism(s) in the carotid body and their physiological importance.
现在已经明确，颈动脉体是监测动脉血氧水平的感觉器官，并触发对低氧血症期间维持体内平衡至关重要的反射。这篇综述文章简要介绍了导致颈动脉体作为感觉受体被发现的早期研究，并阐述了目前对颈动脉体中氧传感机制及其生理重要性的观点。
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