Paediatric Endocrinology Department, Mafraq Hospital , Abu Dhabi, United Arab Emirates .
Diabetes Technol Ther. 2017 Jul;19(7):383-390. doi: 10.1089/dia.2017.0130. Epub 2017 Jul 7.
Toddlers with type 1 diabetes have distinctive combination of challenges to their families and healthcare providers. A major factor is the difficulty in achieving metabolic control without risking hypoglycemia. The rising incidence of type 1 diabetes in toddlers increases the magnitude of the problem and creates a greater need for providing specialized service to cater for this age group's unique need. Type 1 has a specific disease nature in younger children and its clinical presentation mimics common childhood diseases. Symptoms and signs in the newly presented toddler with diabetes might be unspecific causing diagnosis to be missed or delayed. With the low cognitive ability and immature communication, toddlers might not be able to express their ill-feeling resulting from hypoglycemia or hyperglycemia. Hypoglycemia fear is common, which aggravates stress and reduces adherence to strict metabolic control. Nocturnal hypoglycemia is more common in toddlers and can be undiagnosed unless continuous glucose monitoring is used. Insulin administration and adjustment can be challenging due to pain, fear, refusal, and frequent intercurrent illness. Glucose monitoring is crucial. However, it can be distressing to the child and difficult to adhere to due to commitment or financial reasons. Insulin pump therapy is proven to be an effective and a safe method of treatment for toddlers, but it requires intensive training, resources, and long-term support. Provision of multidisciplinary team with special expertise in managing toddlers with diabetes is essential. Providing more physiological insulin regimes and customized technology is required to improve treatment compliance and diabetes control.
1 型糖尿病患儿的家庭和医疗保健提供者面临着独特的挑战组合。一个主要因素是,在不发生低血糖的情况下实现代谢控制非常困难。1 型糖尿病在幼儿中的发病率不断上升,增加了问题的严重性,并需要提供专门的服务来满足这一年龄组的特殊需求。1 型糖尿病在幼儿中有其特定的疾病性质,其临床表现类似于常见的儿童疾病。新出现的糖尿病幼儿的症状和体征可能不特异,导致诊断被遗漏或延迟。由于认知能力低和沟通不成熟,幼儿可能无法表达因低血糖或高血糖引起的不适。低血糖恐惧很常见,这会增加压力,降低对严格代谢控制的依从性。夜间低血糖在幼儿中更为常见,如果不使用连续血糖监测,可能会漏诊。由于疼痛、恐惧、拒绝和频繁的并发疾病,胰岛素的给药和调整可能具有挑战性。血糖监测至关重要。然而,由于承诺或经济原因,这可能会给孩子带来痛苦,并且难以坚持。胰岛素泵治疗已被证明是治疗幼儿的有效和安全方法,但它需要密集的培训、资源和长期支持。提供具有管理幼儿糖尿病专业知识的多学科团队是必不可少的。需要提供更符合生理的胰岛素方案和定制化技术,以提高治疗依从性和糖尿病控制。