de Weert-van Oene Gerdien H, Termorshuizen Fabian, Buwalda Victor J A, Heerdink Eibert R
Arkin Mental Health Amsterdam, Jellinek-Utrecht, ABCstraat 5, 3512 PX, Utrecht, The Netherlands.
Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, PO Box 80082, 3508 TB Utrecht, The Netherlands.
Drug Alcohol Depend. 2017 Sep 1;178:277-284. doi: 10.1016/j.drugalcdep.2017.05.022. Epub 2017 Jun 23.
Patients with substance use disorder (SUD) are frequently suffering from co-occurring somatic disorders, increasing the risk of mortality. Somatic health care utilization (sHCU) often remains unknown to the physician during SUD treatment. This paper analyses sHCU and associated costs among patients in SUD treatment compared to matched, non-substance dependent controls.
Health care utilization data on 4972 SUD patients were matched to 19,846 controls by gender, birth year and ethnic origin. Subcategories of patients were formed based on SUD and on co-morbid psychiatric disorder. Data on sHCU during the year prior to the last treatment contact (the 'index date') for both patients and their matched controls were extracted from a health insurance database.
Patients had a higher sHCU (with increased associated costs) than controls, especially when alcohol dependence was involved. In particular, sHCU for cardiovascular, respiratory, infectious diseases, injuries and accidents was increased among patients. However, the use of preventive medication, such as lipid-lowering drugs, is lower among SUD patients. Co-morbidity of psychiatric disorders led to further increase of sHCU, whereas patients with comorbid non-affective psychotic disorder (NAPD) showed lower sHCU and costs.
Patients with SUD overall have a high sHCU, associated with high costs. There are indications that SUD patients have less access to preventive medication. Patients with comorbid NAPD are at risk of possible underutilization of somatic health care. Furthermore, we conclude that these larger administrative databases allow for comparisons between various diagnostic categories.
物质使用障碍(SUD)患者经常同时患有躯体疾病,这增加了死亡风险。在SUD治疗期间,医生往往并不了解患者的躯体医疗保健利用情况(sHCU)。本文分析了SUD治疗患者与匹配的非物质依赖对照组相比的sHCU及相关费用。
将4972例SUD患者的医疗保健利用数据与19846例对照组按性别、出生年份和种族进行匹配。根据SUD和共病的精神障碍对患者亚组进行分类。从健康保险数据库中提取患者及其匹配对照组在最后一次治疗接触前一年(“索引日期”)的sHCU数据。
患者的sHCU(及相关费用增加)高于对照组,尤其是涉及酒精依赖时。特别是,患者中心血管、呼吸、传染病、损伤和事故方面的sHCU有所增加。然而,SUD患者中预防性药物(如降脂药物)的使用较低。精神障碍共病导致sHCU进一步增加,而患有共病非情感性精神病性障碍(NAPD)的患者sHCU和费用较低。
SUD患者总体上sHCU较高,且费用高昂。有迹象表明SUD患者获得预防性药物的机会较少。患有共病NAPD的患者存在躯体医疗保健利用不足的风险。此外,我们得出结论,这些更大的行政数据库允许对各种诊断类别进行比较。