Lone Farah, Curnow Tamara, Thomas Sarah Anne
Department of Obstetrics and Gynecology, Royal Cornwall Hospital, Truro, UK.
Bodriggy Health Centre, Queensway, Hayle, Cornwall, UK.
Int Urogynecol J. 2018 Jan;29(1):71-79. doi: 10.1007/s00192-017-3405-5. Epub 2017 Jul 7.
Surgical options for uterovaginal prolapse can be categorized into uterus conservation-e.g., laparoscopic sacrohysteropexy (LSHP) or vaginal hysterectomy (VH). There is insufficient reliable information on long-term comparative outcomes of these procedures. The primary aim of this study was to compare subjective and objective outcomes of LSHP and VH. The secondary aim was to record adverse events, recurrent prolapse, and new-onset stress urinary incontinence (SUI) up to 2 years.
Women with symptomatic uterovaginal prolapse who opted for either LSHP or VH were included. Subjective outcomes were compared at 1 and 2 years from baseline using the validated questionnaires. Objective/anatomical outcomes using the Pelvic Organ Prolapse Quantification (POP-Q) system were assessed before and at 3 months after surgery. Adverse events, recurrent prolapse, and new-onset SUI was recorded up to 2 years.
The study assessed 226 women with uterovaginal prolapse; 125 opted for surgery (44 LSHP, 81 VH). There was no statistically significant difference in symptom domains between groups at baseline and 1 and 2 years. At 3 months POP-Q, greater improvement was seen in points Ba and Ap in the LSHP group compared to VH group and smaller genital hiatus was seen in the VH group. Adverse events, recurrent prolapse, or new-onset SUI were not significantly different in the two groups.
Both LSHP and VH are effective surgical options for uterovaginal prolapse. At 2 years, both procedures had similar improvement in symptom domains, overall scores, adverse events, recurrent prolapse, and new-onset SUI. Long-term randomized studies are needed.
子宫阴道脱垂的手术选择可分为保留子宫的手术,例如腹腔镜骶骨子宫固定术(LSHP)或阴道子宫切除术(VH)。关于这些手术长期比较结果的可靠信息不足。本研究的主要目的是比较LSHP和VH的主观和客观结果。次要目的是记录长达2年的不良事件、复发脱垂和新发压力性尿失禁(SUI)。
纳入选择LSHP或VH的有症状子宫阴道脱垂女性。使用经过验证的问卷在基线后1年和2年比较主观结果。在手术前和术后3个月使用盆腔器官脱垂定量(POP-Q)系统评估客观/解剖学结果。记录长达2年的不良事件、复发脱垂和新发SUI。
该研究评估了226例子宫阴道脱垂女性;125例选择手术(44例LSHP,81例VH)。在基线、1年和2年时,两组症状领域无统计学显著差异。在术后3个月的POP-Q中,与VH组相比,LSHP组在Ba点和Ap点有更大改善,VH组的生殖裂孔更小。两组的不良事件、复发脱垂或新发SUI无显著差异。
LSHP和VH都是治疗子宫阴道脱垂的有效手术选择。在2年时,两种手术在症状领域、总体评分、不良事件、复发脱垂和新发SUI方面的改善相似。需要进行长期随机研究。