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婴儿先天性鼻阻塞:一项回顾性研究及文献综述

Congenital nasal obstruction in infants: A retrospective study and literature review.

作者信息

Patel Vijay A, Carr Michele M

机构信息

The Pennsylvania State University, College of Medicine, Department of Surgery, Division of Otolaryngology - Head and Neck Surgery, Hershey, PA, USA.

The Pennsylvania State University, College of Medicine, Department of Surgery, Division of Otolaryngology - Head and Neck Surgery, Hershey, PA, USA.

出版信息

Int J Pediatr Otorhinolaryngol. 2017 Aug;99:78-84. doi: 10.1016/j.ijporl.2017.05.023. Epub 2017 May 30.

DOI:10.1016/j.ijporl.2017.05.023
PMID:28688570
Abstract

OBJECTIVES

To identify etiologies of congenital nasal obstruction and describe clinical practice patterns in the evaluation, diagnosis, and treatment of symptomatic infants.

METHODS

An electronic chart review from 1/1/2006-10/1/2016 for all patients with a diagnosis of nasal obstruction within the first six months of life using ICD-9 and 10 codes 478.19 and J34.89.

RESULTS

A total of 34 patients were evaluated by the Division of Otolaryngology for this chief complaint. 38% of neonates were born premature and 32% were admitted to the NICU at birth, with a female-to-male ratio of 1:1.4. Presenting signs and symptoms included: stertor (44%), cyanosis (24%), stridor (24%), retractions (21%), rhinorrhea (21%), apnea (12%), and epistaxis (8%). 47% of patients received ancillary radiographic imaging (CT or MRI). Diagnoses observed include: midnasal stenosis (38%), pyriform aperture stenosis (21%), choanal stenosis (12%), dacryocystocele (6%), microrhinia (6%), septal deviation (6%), nasopharyngeal reflux (3%), nasopharyngeal teratoma (3%), neonatal rhinitis (3%), and pharyngeal wall collapse (3%). 71% of patients were noted to have bilateral nasal obstruction. 41% of infants were found to have an associated ear, nose, and throat anomaly. 15% of patients required surgical intervention. The mean time-to-resolution was 240 days.

CONCLUSION

Congenital nasal obstruction has a broad differential diagnosis: the timing, onset, and laterality of symptoms can provide insights into the source of upper airway compromise. Most infants improve through conservative management (i.e. suctioning, humidification) and medical therapies (i.e. intranasal drops, nasal sprays).

摘要

目的

确定先天性鼻阻塞的病因,并描述有症状婴儿在评估、诊断和治疗方面的临床实践模式。

方法

对2006年1月1日至2016年10月1日期间所有使用ICD - 9和10编码478.19和J34.89诊断为出生后六个月内鼻阻塞的患者进行电子病历回顾。

结果

耳鼻喉科共对34例以该主诉就诊的患者进行了评估。38%的新生儿早产,32%出生时入住新生儿重症监护病房,男女比例为1:1.4。主要症状和体征包括:喘鸣(44%)、发绀(24%)、喘鸣声(24%)、吸气凹陷(21%)、鼻溢(21%)、呼吸暂停(12%)和鼻出血(8%)。47%的患者接受了辅助影像学检查(CT或MRI)。观察到的诊断包括:鼻中段狭窄(38%)、梨状孔狭窄(21%)、后鼻孔狭窄(12%)、泪囊膨出(6%)、小鼻畸形(6%)、鼻中隔偏曲(6%)、鼻咽反流(3%)、鼻咽畸胎瘤(3%)、新生儿鼻炎(3%)和咽壁塌陷(3%)。71%的患者被发现双侧鼻阻塞。41%的婴儿被发现有相关的耳鼻喉异常。15%的患者需要手术干预。平均缓解时间为240天。

结论

先天性鼻阻塞有广泛的鉴别诊断:症状的时间、发作和侧别可为上气道梗阻的来源提供线索。大多数婴儿通过保守治疗(即吸引、加湿)和药物治疗(即滴鼻剂滴鼻、喷鼻剂)得到改善。

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