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颅内动脉瘤破裂患者动脉瘤血管内栓塞治疗的预后因素

The Prognosis Factors for Endovascular Coiling of Aneurysm in Patients With Ruptured Intracranial Aneurysm.

作者信息

Zhang Feng, Li Peng, Zhang Chao, Wang Li, Jing Shan-Quan

机构信息

*Department of Neurosurgery†Department of Cardiology, The First Hospital of Hebei Medical University, Shijiazhuang, China.

出版信息

J Craniofac Surg. 2017 Sep;28(6):e535-e539. doi: 10.1097/SCS.0000000000003818.

Abstract

BACKGROUND

The spontaneous subarachnoid hemorrhage caused by aneurysm rupture often leads to a variety of complications. Endovascular coiling is effective in the treatment of ruptured intracranial aneurysm.

AIM

The authors aim to evaluate the risk factors affecting the prognosis of ruptured intracranial aneurysm in patients who received endovascular coiling treatment successfully.

METHODS

The demographic and clinical data including age, gender, blood pressure, blood glucose, Hunt-Hess grade, and Fisher grade at admission, Glasgow outcome scale 3 months after coiling, and the location, size of the aneurysms, coiling methods, and time of intervention were retrospectively reviewed and analyzed. Multivariate analysis and logistic regression were used for data analysis.

RESULTS

The history of diabetes mellitus, Hunt-Hess grade, Fisher classification at admission, timing of intervention, as well as the location and size of the aneurysm were prognostic factors for endovascular coiling therapy in patients with ruptured intracranial aneurysm.

CONCLUSION

The Fisher scores, Hunt-Hess classification, history of diabetes mellitus, timing of the intervention, as well as the location and size of aneurysm were independent risk factors for ruptured intracranial aneurysms in patients who received endovascular coiling treatment successfully, which could highly affect the outcome of coiling therapy.

摘要

背景

动脉瘤破裂导致的自发性蛛网膜下腔出血常引发多种并发症。血管内栓塞术在治疗破裂颅内动脉瘤方面有效。

目的

作者旨在评估成功接受血管内栓塞治疗的破裂颅内动脉瘤患者预后的影响因素。

方法

回顾性分析患者的人口统计学和临床资料,包括年龄、性别、血压、血糖、入院时的Hunt-Hess分级和Fisher分级、栓塞术后3个月的格拉斯哥预后量表评分,以及动脉瘤的位置、大小、栓塞方法和干预时间。采用多因素分析和逻辑回归进行数据分析。

结果

糖尿病史、Hunt-Hess分级、入院时的Fisher分级、干预时机以及动脉瘤的位置和大小是破裂颅内动脉瘤患者血管内栓塞治疗的预后因素。

结论

Fisher评分、Hunt-Hess分级、糖尿病史、干预时机以及动脉瘤的位置和大小是成功接受血管内栓塞治疗的破裂颅内动脉瘤患者的独立危险因素,可高度影响栓塞治疗的结果。

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