Dong Mei-Xue, Hu Ling, Huang Yuan-Jun, Xu Xiao-Min, Liu Yang, Wei You-Dong
Department of Neurology, The First Affiliated Hospital of Chongqing Medical University Department of Neurology, The Fifth People's Hospital of Chongqing, Chongqing, China.
Medicine (Baltimore). 2017 Jul;96(28):e7505. doi: 10.1097/MD.0000000000007505.
To determine cerebrovascular risk factors for patients with cerebral watershed infarction (CWI) from Southwest China.Patients suffering from acute ischemic stroke were categorized into internal CWI (I-CWI), external CWI (E-CWI), or non-CWI (patients without CWI) groups. Clinical data were collected and degrees of steno-occlusion of all cerebral arteries were scored. Arteries associated with the circle of Willis were also assessed. Data were compared using Pearson chi-squared tests for categorical data and 1-way analysis of variance with Bonferroni post hoc tests for continuous data, as appropriate. Multivariate binary logistic regression analysis was performed to determine independent cerebrovascular risk factors for CWI.Compared with non-CWI, I-CWI had higher degrees of steno-occlusion of the ipsilateral middle cerebral artery, ipsilateral carotid artery, and contralateral middle cerebral artery. E-CWI showed no significant differences. All the 3 arteries were independent cerebrovascular risk factors for I-CWI confirmed by multivariate binary logistic regression analysis. I-CWI had higher degrees of steno-occlusion of the ipsilateral middle cerebral artery compared with E-CWI. No significant differences were found among arteries associated with the circle of Willis.The ipsilateral middle cerebral artery, carotid artery, and contralateral middle cerebral artery were independent cerebrovascular risk factors for I-CWI. No cerebrovascular risk factor was identified for E-CWI.
确定中国西南地区脑分水岭梗死（CWI）患者的脑血管危险因素。将急性缺血性卒中患者分为内侧脑分水岭梗死（I-CWI）组、外侧脑分水岭梗死（E-CWI）组或非脑分水岭梗死组（无CWI的患者）。收集临床资料并对所有脑动脉的狭窄闭塞程度进行评分。还评估了与 Willis 环相关的动脉。根据情况，分类数据采用 Pearson 卡方检验进行比较，连续数据采用单因素方差分析及 Bonferroni 事后检验进行比较。进行多因素二元逻辑回归分析以确定CWI的独立脑血管危险因素。与非CWI相比，I-CWI同侧大脑中动脉、同侧颈动脉和对侧大脑中动脉的狭窄闭塞程度更高。E-CWI无显著差异。多因素二元逻辑回归分析证实，这3条动脉均为I-CWI的独立脑血管危险因素。与E-CWI相比，I-CWI同侧大脑中动脉的狭窄闭塞程度更高。Willis环相关动脉之间未发现显著差异。同侧大脑中动脉、颈动脉和对侧大脑中动脉是I-CWI的独立脑血管危险因素。未发现E-CWI的脑血管危险因素。
