Galaviz-Silva Lucio, Mercado-Hernández Roberto, Zárate-Ramos José J, Molina-Garza Zinnia J
Universidad Autónoma de Nuevo León (UANL), Facultad de Ciencias Biológicas; Laboratorio de Patología Molecular, San Nicolás de los Garza, Nuevo León, 66451, Mexico.
Universidad Autónoma de Nuevo León (UANL), Facultad de Ciencias Biológicas; Departamento de Ciencias Exactas y Desarrollo Humano, San Nicolás de los Garza, Nuevo León 66451, Mexico.
Rev Argent Microbiol. 2017 Jul-Sep;49(3):216-223. doi: 10.1016/j.ram.2016.11.006. Epub 2017 Jul 10.
Chagas disease, caused by the protozoan Trypanosoma cruzi, is an important public health concern in areas extending from South America northward into the southern United States of America. Although this hemoflagellate has many wild and domestic mammalians reported as reservoir hosts, studies on this subject are scarce in Nuevo León state, a region located in northeastern Mexico. This cross-sectional study showed that the general prevalence of T. cruzi infection in Nuevo León state was 14.5% (35/241), this percentage matching the ones determined by PCR and traditional diagnostics. Localities and infected mammals did not significantly differ (χ=6.098, p=0.192); however the number of infected animals was highly correlated with mammalian species (p=0.009). Striped skunks (Mephitis mephitis) were found to be the most infected overall (11/34, 32.3%), while dogs (Canis familiaris) had the lowest prevalence. In conclusion, although the prevalence of T. cruzi infection in small mammals was lower in Nuevo León than in other states of Mexico, our results provide new locality records, including striped skunks, opossums (Didelphis marsupialis) and dogs, and extend the recorded area to woodrats (Neotoma micropus).
恰加斯病由原生动物克氏锥虫引起，在从南美洲向北延伸至美国南部的地区是一个重要的公共卫生问题。尽管这种血液鞭毛虫有许多野生和家养哺乳动物被报告为储存宿主，但在墨西哥东北部的新莱昂州，关于这一主题的研究却很匮乏。这项横断面研究表明，新莱昂州克氏锥虫感染的总体患病率为14.5%（35/241），这一百分比与通过聚合酶链反应（PCR）和传统诊断方法确定的结果相符。不同地点和受感染的哺乳动物之间没有显著差异（χ=6.098，p=0.192）；然而，受感染动物的数量与哺乳动物物种高度相关（p=0.009）。条纹臭鼬（Mephitis mephitis）总体上感染率最高（11/34，32.3%），而狗（Canis familiaris）的患病率最低。总之，尽管新莱昂州小型哺乳动物中克氏锥虫感染的患病率低于墨西哥其他州，但我们的研究结果提供了新的地点记录，包括条纹臭鼬、负鼠（Didelphis marsupialis）和狗，并将记录区域扩展到林鼠（Neotoma micropus）。
