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短期风险和可治疗性评估(START)对多种不良结局的预测效度:诊断的影响。

Predictive validity of the Short-Term Assessment of Risk and Treatability (START) for multiple adverse outcomes: The effect of diagnosis.

机构信息

Division of Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, London, UK.

Academic Centre, St Andrew's Healthcare, Northampton, UK.

出版信息

Psychiatry Res. 2017 Oct;256:435-443. doi: 10.1016/j.psychres.2017.07.009. Epub 2017 Jul 8.

Abstract

The Short-Term Assessment of Risk and Treatability (START) assists risk assessment for seven risk outcomes based on scoring of risk and protective factors and assignment of clinically-informed risk levels. Its predictive validity for violence and self-harm has been established in males with schizophrenia, but accuracy across pathologically diverse samples is unknown. Routine START assessments and 3-month risk outcome data of N = 527 adult, inpatients in a UK secure mental health facility were collected. The sample was divided into diagnostic groups; predictive validity was established using receiver operating characteristics regression (rocreg) analysis in which potential covariates were controlled. In most single-diagnosis groups START risk factors ('vulnerabilities'), protective factors ('strengths'), and clinically-informed estimates predicted multiple risk outcomes with effect sizes similar to previous research. Self-harm was not predicted among patients with an organic diagnosis. The START risk estimates predicted physical aggression in all diagnostic groups, and verbal aggression, self-harm and self-neglect in most diagnostic groups. The START can assist assessment of aggressive, self-harm, and self-neglect across a range of diagnostic groups. Further research with larger sample sizes of those with multiple diagnoses is required.

摘要

短期风险和可处理性评估(START)通过对风险和保护因素进行评分,并确定临床知情风险水平,有助于对七种风险结果进行风险评估。其对精神分裂症男性的暴力和自残的预测有效性已得到证实,但在病理性差异较大的样本中其准确性尚不清楚。研究收集了英国一家安全心理健康机构中 527 名成年住院患者的常规 START 评估和 3 个月的风险结果数据。该样本被分为诊断组;使用接收器操作特征回归(rocreg)分析确定预测有效性,其中控制了潜在的协变量。在大多数单一诊断组中,START 风险因素(“脆弱性”)、保护因素(“优势”)和临床知情估计可预测多种风险结果,其效应大小与先前的研究相似。器质性诊断患者中未预测到自残。START 风险估计可预测所有诊断组中的身体攻击,以及大多数诊断组中的言语攻击、自残和自我忽视。START 可帮助评估多种诊断组的攻击、自残和自我忽视风险。需要对具有多种诊断的患者进行更大样本量的进一步研究。

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