Iqbal Javed, Khan Faridullah, Abbasi Saleem, Abid Abdul Rehman
Department of Cardiac Surgery, Pakistan Institute of Medical Sciences, SZABMU, Islamabad, Pakistan.
ARI Research Cell, Children Hospital, Pakistan Institute of Medical Sciences, SZABMU, Islamabad, Pakistan.
J Ayub Med Coll Abbottabad. 2016 Jul-Sep;28(3):471-475.
Respiratory problems are one of the major issues faced by cardiovascular surgeons, which increase morbidity and mortality among patients undergoing coronary artery bypass grafting (CABG). It is possible to harvest the left internal mammary artery (LIMA) without opening the left pleura; however this cannot be reliably achieved in all cases due to intimate anatomical relationship. This study was designed to evaluate the effect of internal mammary artery harvesting with and without pleurotomy on respiratory complications in patients undergoing coronary artery bypass grafting.
In this observational study 90 patients who underwent coronary artery bypass surgery were included by review of records. Patients were stratified into two groups according to surgical procedures, i.e., Internal Mammary artery harvesting with pleurotomy; (WP Group) (n=45) and with extra pleural harvesting technique; (EP Group) (n=45). Inclusion criteria were elective coronary artery bypass grafting, age over 18 years, willingness to be randomly assigned, provision of informed consent. Exclusion criteria were chronic obstructive pulmonary disease (COPD) or skeletal abnormalities that caused pulmonary restriction. Only the first 30 days postoperative outcome was studied. Data was analysed using SPSS version 21.
The demographic characteristics in terms of age and gender were comparable in study groups. The preoperative clinical presentation and medical history were also found similar. The hospital stay was significantly longer in WP Group than EP Group patients (7.2 vs 6.1 days, p<0.005). Moreover, post-operative morbidity was more prevalent in WP group 10 (22.2%) than EP Group 3 (66%) (p<0.03). In WP Group more respiratory complications were observed; 2 (4.4%) patients had dry cough and atelectasis, 1 (2.2%) patient experienced pleural effusion, 3 (6.6%) had bronchospasm while 1 (2.2%) patient each had sternal dehiscence and bleeding, however, these did not differ significantly among study groups.
Respiratory complications were more frequent in patients undergoing Internal Mammary artery harvesting with pleurotomy compared to those managed extra pleural harvesting.
呼吸问题是心血管外科医生面临的主要问题之一,这会增加接受冠状动脉旁路移植术(CABG)患者的发病率和死亡率。不打开左胸膜就有可能获取左乳内动脉(LIMA);然而,由于密切的解剖关系,并非所有病例都能可靠地做到这一点。本研究旨在评估在冠状动脉旁路移植术患者中,采用和不采用胸膜切开术获取乳内动脉对呼吸并发症的影响。
在这项观察性研究中,通过查阅记录纳入了90例行冠状动脉旁路手术的患者。根据手术方式将患者分为两组,即采用胸膜切开术获取乳内动脉组(WP组)(n = 45)和采用胸膜外获取技术组(EP组)(n = 45)。纳入标准为择期冠状动脉旁路移植术、年龄超过18岁、愿意随机分组、提供知情同意书。排除标准为慢性阻塞性肺疾病(COPD)或导致肺部受限的骨骼异常。仅研究术后前30天的结果。使用SPSS 21版软件进行数据分析。
研究组在年龄和性别方面的人口统计学特征具有可比性。术前临床表现和病史也相似。WP组患者的住院时间明显长于EP组患者(7.2天对6.1天,p < 0.005)。此外,WP组术后发病率(10例,22.2%)高于EP组(3例,6.6%)(p < 0.03)。在WP组观察到更多的呼吸并发症;2例(4.4%)患者出现干咳和肺不张,1例(2.2%)患者出现胸腔积液,3例(6.6%)出现支气管痉挛,而各有1例(2.2%)患者出现胸骨裂开和出血,然而,这些在研究组之间没有显著差异。
与采用胸膜外获取技术的患者相比,采用胸膜切开术获取乳内动脉的患者呼吸并发症更频繁。