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从现代疼痛生理学知识角度看分娩疼痛

[Labor pain from the viewpoint of the modern knowledge of pain physiology].

作者信息

Frahm R, Mundt A

出版信息

Zentralbl Gynakol. 1986;108(4):203-11.

PMID:2871674
Abstract

The valuation and treatment of labor pains require complete morphological and anatomical informations about the neuronal systems concerned. A review is given about modern model conceptions in perception, modulation and transmission of pain, based on the latest knowledges in the pain research. The identification of central control- and modulation systems is very important for the actual theory of pain. Pains and also labor pains are caused as a result of complicated nerval connective principles with slim relation to endocrinological system and are also connected with a lot of individual psychical influences. Essentially, four functional stages are passed from the place of nociceptive perception to the registration in the telencephalon. These are depicted in consideration of numerous afferent and efferent, biochemical and hormonal, stimulated and inhibited modulation effects. Various pain inhibitory mechanisms, such as biogenic amines and endogenous opioids are discussed by reference to interesting aspects in new therapeutical possibilities in treatment of pain and also of labor pains.

摘要

分娩疼痛的评估和治疗需要有关相关神经系统的完整形态学和解剖学信息。基于疼痛研究的最新知识,对疼痛感知、调节和传递的现代模型概念进行了综述。中枢控制和调节系统的识别对于当前的疼痛理论非常重要。疼痛以及分娩疼痛是由与内分泌系统关系不大的复杂神经连接原理引起的,并且还与许多个体心理影响有关。从伤害性感知部位到端脑的记录,基本上要经过四个功能阶段。这些阶段是在考虑到众多传入和传出、生化和激素、刺激和抑制调节作用的情况下描绘的。通过参考疼痛和分娩疼痛治疗新疗法中有趣的方面,讨论了各种疼痛抑制机制,如生物胺和内源性阿片类物质。

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