Pathak Vikas, Allender J Erin, Grant Mollie W
Dept of Pulmonary Disease and Critical Care Medicine, WakeMed Health and Hospitals, Raleigh, NC, USA
Dept of Pharmacy, WakeMed Health and Hospitals, Raleigh, NC, USA.
Eur Respir Rev. 2017 Jul 19;26(145). doi: 10.1183/16000617.0020-2017. Print 2017 Sep 30.
There has been great progress in antithrombotic therapy over the past several years. Its use has increased with the advent of novel anticoagulants, as these medications do not require frequent blood tests for monitoring. Antithrombotic therapy is aimed at reducing the risk of thromboembolic events in patients with atrial fibrillation, coronary artery disease, deep vein thrombosis, valvular heart disease and pulmonary embolism. These patients are often critically ill and frequently undergo urgent interventions requiring discontinuation of anticoagulant or antiplatelet therapy which can increase the risk of thrombosis; however, continuing these agents can lead to increased risk of haemorrhage.The purpose of this article is to summarise the literature surrounding the safety of using antiplatelet and anticoagulant therapies in patients undergoing interventional pulmonary procedures.
在过去几年中,抗栓治疗取得了巨大进展。随着新型抗凝剂的出现,其使用有所增加,因为这些药物不需要频繁进行血液检测来监测。抗栓治疗旨在降低心房颤动、冠状动脉疾病、深静脉血栓形成、心脏瓣膜病和肺栓塞患者发生血栓栓塞事件的风险。这些患者通常病情危急,经常需要进行紧急干预,这就需要停用抗凝或抗血小板治疗,而这可能会增加血栓形成的风险;然而,继续使用这些药物会导致出血风险增加。本文的目的是总结有关在接受介入性肺部手术的患者中使用抗血小板和抗凝治疗安全性的文献。