在一只接受尿动力学研究和经皮脊髓刺激的恒河猴（猕猴）中，全身惊厥性癫痫发作与氯胺酮麻醉有关。
Generalized convulsive seizures are associated with ketamine anesthesia in a rhesus macaque (Macaca mulatta) undergoing urodynamic studies and transcutaneous spinal cord stimulation.
作者信息
Gad Parag N, Salyards Gregory W, Garzel Laura M, Christe Kari L, Edgerton V Reggie, Havton Leif A
机构信息
Department of Integrative Biology and Physiology, University of California, Los Angeles, CA, USA.
California National Primate Research Center, University of California, Davis, CA, USA.
出版信息
J Med Primatol. 2017 Dec;46(6):359-363. doi: 10.1111/jmp.12287. Epub 2017 Jul 20.
Abstract
A female rhesus macaque developed two episodes of generalized convulsions during transcutaneous spinal cord stimulation (TSCS) and urodynamic studies under ketamine anesthesia. The seizures took place in the absence of active TSCS and bladder pressure elevation. Ketamine anesthesia remains the primary risk factor for the convulsions during these experimental procedures.
摘要
一只雌性恒河猴在氯胺酮麻醉下进行经皮脊髓刺激（TSCS）和尿动力学研究期间发生了两次全身性惊厥。惊厥发作时TSCS未激活且膀胱压力未升高。氯胺酮麻醉仍然是这些实验过程中惊厥发作的主要危险因素。
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