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精神分裂症预后的预测因素:过程-反应维度

Predictors of outcome in schizophrenia: the process-reactive dimension.

作者信息

Harrow M, Westermeyer J F, Silverstein M, Strauss B S, Cohler B J

出版信息

Schizophr Bull. 1986;12(2):195-207. doi: 10.1093/schbul/12.2.195.

Abstract

Premorbid social-sexual competence and the process-reactive dimension, as assessed by the Phillips Scale, were investigated as predictors of posthospital adjustment in a prospective study of two samples of 141 young, early phase schizophrenics (a private hospital sample and a state hospital sample). The Phillips Scale predicted subsequent outcome at significant levels for one of the two samples of DSM-II schizophrenics (a "broad" construct of schizophrenia). It did not predict outcome as well for DSM-III schizophrenics (a "narrow" construct of schizophrenia). Mixed results emerged from separate analyses of first-admission schizophrenics only and for male schizophrenics only. The data indicated that marital status accounts for some of the positive relationship between the Phillips Scale and later outcome. A more focused measure of prehospital social adjustment successfully predicted social functioning at followup for both DSM-II and DSM-III schizophrenics (p less than .05). There were some significant and near-significant relationships, but overall results suggest that when the influence of chronicity and marital status is reduced, the relationship between the Phillips Scale and subsequent outcome is less robust than was once thought.

摘要

在一项针对141名年轻的早期精神分裂症患者的两个样本(一个私立医院样本和一个州立医院样本)的前瞻性研究中,研究了病前社会-性能力以及由菲利普斯量表评估的过程反应维度,作为出院后适应情况的预测指标。菲利普斯量表在DSM-II精神分裂症患者的两个样本之一(一种“宽泛”的精神分裂症概念)中,能在显著水平上预测后续结果。但对于DSM-III精神分裂症患者(一种“狭义”的精神分裂症概念),其预测效果则没那么好。仅对首次入院的精神分裂症患者以及仅对男性精神分裂症患者进行单独分析时,得出了混合结果。数据表明,婚姻状况在菲利普斯量表与后期结果之间的部分正向关系中起到了作用。一种更具针对性的病前社会适应测量方法成功预测了DSM-II和DSM-III精神分裂症患者随访时的社会功能(p小于0.05)。存在一些显著和接近显著的关系,但总体结果表明,当病程和婚姻状况的影响降低时,菲利普斯量表与后续结果之间的关系并不像曾经认为的那样稳固。

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