Moon T, Lin R Y, Jahn A F
J Otolaryngol. 1986 Jun;15(3):193-5.
Infectious sinusitis may on occasion be associated with meningitis, subdural empyema, epidural empyema, brain abscess, or osteomyelitis. We report a 29-year-old male patient with frontal sinusitis who developed all of these intracranial complications due to two previously unreported causative organisms, Neisseria sicca and Eubacterium lentum. The fulminant and fatal course resulting from locally invasive disease underscores the importance of early diagnosis and proper treatment of these complications. Possible exacerbating factors in this patient were sickle cell disease and immune compromise due to intravenous drug abuse.
感染性鼻窦炎有时可能与脑膜炎、硬膜下积脓、硬膜外积脓、脑脓肿或骨髓炎相关。我们报告一名29岁的额窦炎男性患者，因两种此前未报道的病原体——干燥奈瑟菌和迟缓真杆菌，而出现了所有这些颅内并发症。局部侵袭性疾病导致的暴发性和致命病程凸显了对这些并发症进行早期诊断和恰当治疗的重要性。该患者可能的加重因素为镰状细胞病和静脉药物滥用导致的免疫功能受损。
