Piva Roberta, Ticconi Flavia, Ceriani Valentina, Scalorbi Federica, Fiz Francesco, Capitanio Selene, Bauckneht Matteo, Cittadini Giuseppe, Sambuceti Gianmario, Morbelli Silvia
Nuclear Medicine Unit, Department of Health Sciences, University of Genoa, Genoa.
Nuclear Medicine Unit, S. Orsola-Malpighi University Hospital, Bologna.
Breast Cancer (Dove Med Press). 2017 Jul 4;9:461-471. doi: 10.2147/BCTT.S111098. eCollection 2017.
In the last decades, in addition to conventional imaging techniques and magnetic resonance imaging (MRI), F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) has been shown to be relevant in the detection and management of breast cancer recurrence in doubtful cases in selected groups of patients. While there are no conclusive data indicating that imaging tests, including FDG PET/CT, produce a survival benefit in asymptomatic patients, FDG PET/CT can be useful for identifying the site of relapse when traditional imaging methods are equivocal or conflicting and for identifying or confirming isolated loco-regional relapse or isolated metastatic lesions. The present narrative review deals with the potential role of FDG PET in these clinical settings by comparing its accuracy and impact with conventional imaging modalities such as CT, ultrasound, bone scan, F-sodium fluoride PET/CT (F-NaF PET/CT) as well as MRI. Patient-focused perspectives in terms of patients' satisfaction and acceptability are also discussed.
在过去几十年中，除了传统成像技术和磁共振成像（MRI）外，氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG PET/CT）已被证明在特定患者群体的可疑病例中，对乳腺癌复发的检测和管理具有重要意义。虽然没有确凿数据表明包括FDG PET/CT在内的成像检查能使无症状患者获得生存益处，但当传统成像方法结果不明确或相互矛盾时，FDG PET/CT有助于确定复发部位，还可用于识别或确认孤立的局部区域复发或孤立的转移病灶。本叙述性综述通过比较FDG PET与CT、超声、骨扫描、氟氟化钠PET/CT（F-NaF PET/CT）以及MRI等传统成像方式的准确性和影响，探讨了FDG PET在这些临床场景中的潜在作用。还讨论了从患者满意度和可接受性等方面以患者为中心的观点。
