Lambert Kelly, Beer Jo, Dumont Ruth, Hewitt Katie, Manley Karen, Meade Anthony, Salamon Karen, Campbell Katrina
Department of Clinical Nutrition, Wollongong Hospital, Illawarra Shoalhaven Local Health District, Wollongong, New South Wales, Australia.
Younger Adult Rehabilitation Department, Osborne Park Hospital, Stirling, Western Australia, Australia.
Nephrology (Carlton). 2018 Oct;23(10):912-920. doi: 10.1111/nep.13118.
The aim of the present study was to develop a consensus report to guide dietetic management of overweight or obese individuals with chronic kidney disease (CKD).
Six statements relating to weight management in CKD guided a comprehensive review of the literature. A summary of the evidence was then presented at the renal nutrition meeting of the 2016 Asia Pacific Society of Nephrology and Australia and New Zealand Society of Nephrology. Majority agreement was defined as group agreement on a statement of between 50-74%, and consensus was considered ≥75% agreement. The recommendations were developed via a mini Delphi process.
Two statements achieved group consensus: the current guidelines used by dietitians to estimate energy requirements for overweight and obese people with CKD are not relevant and weight loss medications may be unsafe or ineffective in isolation for those with CKD. One statement achieved group agreement: Meal replacement formulas are safe and efficacious in those with CKD. No agreement was achieved on the statements of whether there is strong evidence of benefit for weight loss prior to kidney transplantation; whether traditional weight loss strategies can be used in those with CKD and if bariatric surgery in those with end stage kidney disease is feasible and effective.
There is a limited evidence base to guide the dietetic management of overweight and obese individuals with CKD. Medical or surgical strategies to facilitate weight loss are not recommended in isolation and require a multidisciplinary approach with the involvement of a skilled renal dietitian.
本研究旨在制定一份共识报告,以指导对患有慢性肾脏病(CKD)的超重或肥胖个体的饮食管理。
与CKD患者体重管理相关的六项声明指导了对文献的全面综述。然后,证据总结在2016年亚太肾脏病学会和澳大利亚及新西兰肾脏病学会的肾脏营养会议上进行了展示。多数同意被定义为对某一声明的群体同意率在50%-74%之间,而共识则被认为是同意率≥75%。这些建议是通过一个小型德尔菲法制定的。
两项声明达成了群体共识:营养师目前用于估计CKD超重和肥胖患者能量需求的指南不适用,并且减肥药物单独使用对CKD患者可能不安全或无效。一项声明达成了群体同意:代餐配方食品对CKD患者是安全有效的。对于肾移植前是否有强有力的证据表明减肥有益;CKD患者是否可以使用传统的减肥策略;以及终末期肾病患者进行减肥手术是否可行和有效等声明,未达成一致意见。
指导CKD超重和肥胖个体饮食管理的证据基础有限。不建议单独使用促进减肥的医学或手术策略,而是需要多学科方法,包括专业肾脏营养师的参与。