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通过症状驱动的血管和影像学研究评估骨科创伤患者适当的静脉血栓栓塞预防措施。

Evaluation of Appropriate Venous Thromboembolism Prophylaxis in Patients With Orthopaedic Trauma With Symptom-Driven Vascular and Radiographic Studies.

作者信息

Domes Christopher M, Schleyer Anneliese M, McQueen James M, Pergamit Ronald F, Beingessner Daphne M

机构信息

Departments of Orthopaedics and Sports Medicine.

Medicine, and.

出版信息

J Orthop Trauma. 2017 Dec;31(12):611-616. doi: 10.1097/BOT.0000000000000991.

Abstract

OBJECTIVE

To evaluate venous thromboembolism (VTE) prophylaxis adherence and effectiveness in orthopaedic trauma patients who had vascular or radiographic studies showing deep vein thromboses or pulmonary emboli.

DESIGN

Retrospective review.

SETTING

A level I trauma center that independently services a 5-state region.

PATIENTS

Four hundred seventy-six patients with orthopaedic trauma who underwent operative treatments for orthopaedic injuries and had symptom-driven diagnostic VTE studies.

INTERVENTION

The medical records of patients treated surgically between July 2010 and March 2013 were interrogated using a technical tool that electronically captures thrombotic event data from vascular and radiologic imaging studies by natural language processing.

MAIN OUTCOME MEASUREMENTS

Patients were evaluated for hospital guideline-directed VTE prophylaxis adherence with mechanical or chemical prophylaxis. Patient demographics, associated injuries, mechanism of injury, and symptoms that led to imaging for a VTE were also assessed.

RESULTS

Of the 476 orthopaedic patients who met inclusion criteria, 100 (mean age 52.3 median 52, SD 18.3, 70% men) had positive VTE studies. Three hundred seventy-six (age 47.3, SD 17.3, 69% men) had negative VTE studies. Of the 100 patients with VTE, 63 deep vein thromboses, and 49 pulmonary emboli were found. Eight-five percent of all patients met hospital guideline-VTE prophylaxis standards.

CONCLUSION

The study population had better than previously reported VTE prophylaxis adherence, however, patients still developed VTEs.

LEVEL OF EVIDENCE

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

摘要

目的

评估血管检查或影像学检查显示有深静脉血栓形成或肺栓塞的骨科创伤患者的静脉血栓栓塞(VTE)预防依从性及有效性。

设计

回顾性研究。

地点

一个独立服务于五州地区的一级创伤中心。

患者

476例接受骨科损伤手术治疗且进行了症状驱动的VTE诊断性检查的骨科创伤患者。

干预措施

使用一种技术工具对2010年7月至2013年3月间接受手术治疗的患者的病历进行审查,该工具通过自然语言处理从血管和放射影像研究中电子捕获血栓形成事件数据。

主要观察指标

评估患者对医院指南指导的机械或药物VTE预防的依从性。还评估了患者的人口统计学特征、相关损伤、损伤机制以及导致VTE影像学检查的症状。

结果

在符合纳入标准的476例骨科患者中,100例(平均年龄52.3岁,中位数52岁,标准差18.3,70%为男性)VTE检查呈阳性。376例(年龄47.3岁,标准差17.3,69%为男性)VTE检查呈阴性。在100例VTE患者中,发现63例深静脉血栓形成和49例肺栓塞。所有患者中有85%符合医院指南的VTE预防标准。

结论

研究人群的VTE预防依从性优于先前报道,但患者仍发生了VTE。

证据级别

预后三级。有关证据级别的完整描述,请参阅作者指南。

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