Mahmoudi Shima, Pourakbari Babak, Borhani Katayoun, Khodabandeh Mahmoud, Valian Sepideh Keshavarz, Aziz-Ahari Alireza, Mamishi Setareh
Pediatric Infectious Diseases Research Center, Tehran University of Medical Sciences, No. 62, Dr. Gharib St., Tehran, Iran.
Department of Infectious Diseases, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Wien Med Wochenschr. 2017 Sep;167(11-12):259-263. doi: 10.1007/s10354-017-0583-1. Epub 2017 Jul 25.
Information concerning the epidemiology of acute osteomyelitis (OM), septic arthritis (SA) and concurrent OM and SA in children is limited. The aim of this study was to describe the epidemiology of OM, SA and concurrent OM and SA in children. During the 4 years of the study, 63,999 patients were admitted to the Children's Hospital, Tehran, Iran. We identified 111 patients with OM and/or SA during the 4‑year period. There were 72 cases of OM (11 cases per 10,000 children) and 90 cases of SA (11 cases per 10,000 children). Concurrent OM and SA accounted for 0.17% of all cases (n = 51). The erythrocyte sedimentation rate and C‑reactive protein were elevated in the majority of both infections. Staphylococcus aureus was the most frequent pathogen responsible for both OM and SA in any age group. The lower limb was the most frequently affected (femur: 33/72, 46%; tibia or fibula: 22/72, 31%; foot: 5/72, 7%). The most frequent involved joints were hips (n = 31, 34%) and knees (n = 31, 34%). The present study showed high frequency of patients with concurrent SA and OM. Therefore, prompt recognition and proper diagnosis of pediatric OM and SA is highly recommended.
关于儿童急性骨髓炎（OM）、脓毒性关节炎（SA）以及并发的OM和SA的流行病学信息有限。本研究的目的是描述儿童OM、SA以及并发的OM和SA的流行病学情况。在该研究的4年期间，63999名患者入住伊朗德黑兰儿童医院。我们在这4年期间确定了111例患有OM和/或SA的患者。其中有72例OM（每10000名儿童中有11例）和90例SA（每10000名儿童中有11例）。并发的OM和SA占所有病例的0.17%（n = 51）。在这两种感染中，大多数患者的红细胞沉降率和C反应蛋白都升高。金黄色葡萄球菌是任何年龄组中导致OM和SA的最常见病原体。下肢是最常受累的部位（股骨：33/72，46%；胫骨或腓骨：22/72，31%；足部：5/72，7%）。最常受累的关节是髋关节（n = 31，34%）和膝关节（n = 31，34%）。本研究显示并发SA和OM的患者频率较高。因此，强烈建议对儿童OM和SA进行及时识别和正确诊断。
