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农村地区及物质使用对超高精神疾病风险青少年的影响。

Impact of rurality and substance use on young people at ultra high risk for psychosis.

作者信息

Stain Helen J, Halpin Sean A, Baker Amanda L, Startup Mike, Carr Vaughan J, Schall Ulrich, Crittenden Kylie, Clark Vanessa, Lewin Terry J, Bucci Sandra

机构信息

School of Medicine, Pharmacy and Health, Durham University, Durham, UK.

School of Psychology, University of Newcastle, Newcastle, New South Wales, Australia.

出版信息

Early Interv Psychiatry. 2018 Dec;12(6):1173-1180. doi: 10.1111/eip.12437. Epub 2017 Jul 26.

Abstract

BACKGROUND

Longitudinal research into early intervention for youth at ultra high risk (UHR) for psychosis demonstrates beneficial outcomes including increased treatment compliance and greater participation in education and the workforce. Despite known barriers for rural youth accessing mental health services, research comparing urban and rural UHR youth is lacking. The study included an examination of the impact of substance use on functioning of UHR youth.

METHODS

Youth aged 12 to 25 years were recruited from the urban area of Newcastle or the rural area of Orange, New South Wales, Australia, and identified as UHR by the Comprehensive Assessment of At Risk Mental States. Rural and urban youth were compared on clinical profiles, social and occupational functioning and substance use.

RESULTS

The rural youth showed different help-seeking behaviours and had greater functional impairment than urban youth. Substance use was common across the sample of 57 youth (mean age 16.5 years, 56% female) and a history of hazardous substance use was associated with higher levels of depression. Rural youth (n = 32) were more likely than urban youth to be taking antidepressants at baseline (44% compared with 16%).

CONCLUSION

Different patterns of help seeking by rural UHR youth suggest a need for greater access to psychosis informed primary care early intervention services. Interventions should target functional decline to prevent adverse outcomes such as reduced community participation and unemployment. In addition, interventions for substance use should be a priority for UHR youth, who should also be screened and monitored for depressive symptoms and treated for depression if indicated.

摘要

背景

对超高危(UHR)精神病青年进行早期干预的纵向研究表明,其有益结果包括治疗依从性提高以及教育和劳动力参与度增加。尽管农村青年在获得心理健康服务方面存在已知障碍,但缺乏比较城市和农村UHR青年的研究。该研究包括考察物质使用对UHR青年功能的影响。

方法

从澳大利亚新南威尔士州纽卡斯尔市区或奥兰治农村地区招募12至25岁的青年,并通过高危精神状态综合评估确定为UHR。比较农村和城市青年的临床特征、社会和职业功能以及物质使用情况。

结果

农村青年表现出不同的求助行为,且功能损害比城市青年更大。在57名青年(平均年龄16.5岁,56%为女性)样本中,物质使用很常见,有害物质使用史与更高水平的抑郁相关。农村青年(n = 32)在基线时比城市青年更有可能服用抗抑郁药(分别为44%和16%)。

结论

农村UHR青年不同的求助模式表明需要更多地获得针对精神病的初级保健早期干预服务。干预应针对功能衰退,以预防社区参与减少和失业等不良后果。此外,物质使用干预应成为UHR青年的优先事项,还应对他们进行抑郁症状筛查和监测,如有指征应进行抑郁治疗。

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