Rodgers S, Vandeleur C L, Strippoli M-P F, Castelao E, Tesic A, Glaus J, Lasserre A M, Müller M, Rössler W, Ajdacic-Gross V, Preisig M
Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, PO Box 1930, 8021, Zurich, Switzerland.
Epidemiology, Biostatistics and Prevention Institute, Swiss MS Registry, University of Zurich, Zurich, Switzerland.
Soc Psychiatry Psychiatr Epidemiol. 2017 Sep;52(9):1169-1182. doi: 10.1007/s00127-017-1421-x. Epub 2017 Jul 26.
Given the broad range of biopsychosocial difficulties resulting from major depressive disorder (MDD), reliable evidence for predictors of improved mental health is essential, particularly from unbiased prospective community samples. Consequently, a broad spectrum of potential clinical and non-clinical predictors of improved mental health, defined as an absence of current major depressive episode (MDE) at follow-up, were examined over a 5-year period in an adult community sample.
The longitudinal population-based PsyCoLaus study from the city of Lausanne, Switzerland, was used. Subjects having a lifetime MDD with a current MDE at baseline assessment were selected, resulting in a subsample of 210 subjects. Logistic regressions were applied to the data.
Coping styles were the most important predictive factors in the present study. More specifically, low emotion-oriented coping and informal help-seeking behaviour at baseline were associated with the absence of an MDD diagnosis at follow-up. Surprisingly, neither formal help-seeking behaviour, nor psychopharmacological treatment, nor childhood adversities, nor depression subtypes turned out to be relevant predictors in the current study.
The paramount role of coping styles as predictors of improvement in depression found in the present study might be a valuable target for resource-oriented therapeutic models. On the one hand, the positive impact of low emotion-oriented coping highlights the utility of clinical interventions interrupting excessive mental ruminations during MDE. On the other hand, the importance of informal social networks raises questions regarding how to enlarge the personal network of affected subjects and on how to best support informal caregivers.
鉴于重度抑郁症(MDD)会引发广泛的生物心理社会问题,因此获得心理健康改善预测因素的可靠证据至关重要,特别是来自无偏倚的前瞻性社区样本的证据。因此,在一个成年社区样本中,对一系列广泛的心理健康改善潜在临床和非临床预测因素进行了为期5年的研究,心理健康改善定义为随访时无当前重度抑郁发作(MDE)。
采用了瑞士洛桑市基于人群的纵向PsyCoLaus研究。选择在基线评估时有终生MDD且当前有MDE的受试者,得到一个210名受试者的子样本。对数据应用逻辑回归。
应对方式是本研究中最重要的预测因素。更具体地说,基线时低情绪导向应对和非正式求助行为与随访时无MDD诊断相关。令人惊讶的是,在本研究中,正式求助行为、心理药物治疗、童年逆境和抑郁亚型均未成为相关预测因素。
本研究发现应对方式作为抑郁症改善预测因素的首要作用可能是资源导向治疗模式的一个有价值目标。一方面,低情绪导向应对的积极影响突出了临床干预在MDE期间中断过度心理反刍的效用。另一方面,非正式社会网络的重要性引发了关于如何扩大受影响受试者的个人网络以及如何最好地支持非正式照顾者的问题。