University of Kansas, United States.
University of Kansas, United States.
Compr Psychiatry. 2017 Nov;79:40-52. doi: 10.1016/j.comppsych.2017.06.009. Epub 2017 Jun 28.
Several problems with the classification and diagnosis of eating disorders (EDs) have been identified, including proliferation of 'other specified' diagnoses, within-disorder heterogeneity, and frequent diagnostic migration over time. Beyond problems within EDs, past research suggested that EDs fit better in a spectrum of internalizing psychopathology (characterized by mood and anxiety disorders) than in a separate diagnostic class.
To develop a transdiagnostic, hierarchical-dimensional model relevant to ED psychopathology that: 1) reduces diagnostic heterogeneity, 2) includes important dimensions of internalizing psychopathology that are often excluded from ED diagnostic models, and 3) predicts clinical impairment.
Goldberg's (2006) method and exploratory structural equation modeling were used to identify a hierarchical model of internalizing in community-recruited adults with EDs (N=207).
The lowest level of the hierarchy was characterized by 15 factors that defined specific aspects of eating, mood, and anxiety disorders. At the two-factor level, Internalizing bifurcated into Distress (low well-being, body dissatisfaction, suicidality, dysphoria, ill temper, traumatic intrusions) and Fear-Avoidance (claustrophobia, social avoidance, panic symptoms, dietary restricting, excessive exercise, and compulsions). Results showed that the lowest level of the hierarchy predicted 67.7% of the variance in clinical impairment. In contrast, DSM eating, mood, and anxiety disorders combined predicted 10.6% of the variance in impairment secondary to an ED.
The current classification model represents an improvement over traditional nosologies for predicting clinically relevant outcomes for EDs.
已经发现了一些与进食障碍(EDs)的分类和诊断相关的问题,包括“其他特定”诊断的扩散、疾病内异质性以及随时间频繁的诊断迁移。除了 ED 内的问题外,过去的研究表明,ED 更适合在内向性精神病理学(以情绪和焦虑障碍为特征)的范围内,而不是在单独的诊断类别中。
开发与 ED 病理相关的跨诊断、层次维度模型,该模型:1)减少诊断异质性,2)包含常被 ED 诊断模型排除的重要的内向性精神病理学维度,以及 3)预测临床损伤。
采用戈德堡(2006)的方法和探索性结构方程模型,对社区招募的 ED 成人(N=207)进行了内在化的层次模型识别。
层次结构的最低级别由 15 个因素定义,这些因素定义了饮食、情绪和焦虑障碍的具体方面。在双因素水平上,内向性分为痛苦(低幸福感、身体不满、自杀意念、情绪低落、脾气暴躁、创伤性侵入)和恐惧回避(幽闭恐惧症、社交回避、恐慌症状、饮食限制、过度运动和强迫)。结果表明,层次结构的最低级别预测了 67.7%的临床损伤的变异性。相比之下,DSM 饮食、情绪和焦虑障碍的组合仅预测了 ED 导致的损伤的 10.6%的变异性。
与传统的分类学相比,当前的分类模型在预测 ED 的临床相关结果方面有所改进。