巯基琥珀酸包覆的近红外发射金纳米颗粒用于汞的灵敏和选择性检测。

Mercaptosuccinic acid-coated NIR-emitting gold nanoparticles for the sensitive and selective detection of Hg.

作者信息

Xiong Xiaodong, Lai Xiaoqi, Liu Jinbin

机构信息

Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China; School of Chemistry and Chemical Engineering, Gannan Normal University, Ganzhou 341000, China.

School of Chemistry and Chemical Engineering, Gannan Normal University, Ganzhou 341000, China.

出版信息

Spectrochim Acta A Mol Biomol Spectrosc. 2018 Jan 5;188:483-487. doi: 10.1016/j.saa.2017.07.035. Epub 2017 Jul 23.

DOI:10.1016/j.saa.2017.07.035

PMID:28759849

Abstract

A sensitive fluorescent detection platform for Hg was constructed based on mercaptosuccinic acid (MSA) coated near-infrared (NIR)-emitting gold nanoparticles (AuNPs). The thiolated mercaptosuccinic acid was employed as both reducing agent and surface coating ligand in a one-step synthesis of NIR-emitting AuNPs (MSA-AuNPs), which exhibited stable fluorescence with the maximum wavelength at 800nm and a wide range of excitation (220-650nm) with the maxima at 413nm. The MSA coated NIR-emitting AuNPs showed a rapid fluorescence quenching toward Hg over other metal ions with a limit of detection (LOD, 3δ) as low as 4.8nM. The sensing mechanism investigation revealed that the AuNPs formed aggregation due to the "recognition" of Hg from the MSA, and the resultant strong coupling interaction between Hg and Au (I) to further quench the fluorescence of the AuNPs, which synergistically resulted in a highly sensitive and selective fluorescence response toward Hg. This proposed strategy was also demonstrated the possibility to be used for Hg detection in water samples.

摘要

基于巯基琥珀酸（MSA）包覆的近红外（NIR）发射金纳米粒子（AuNPs）构建了一种用于汞的灵敏荧光检测平台。在一步合成近红外发射金纳米粒子（MSA-AuNPs）过程中，硫醇化的巯基琥珀酸既用作还原剂又用作表面包覆配体，该金纳米粒子表现出稳定的荧光，最大波长为800nm，激发范围宽（220 - 650nm），最大激发波长为413nm。与其他金属离子相比，MSA包覆的近红外发射金纳米粒子对汞表现出快速的荧光猝灭，检测限（LOD，3δ）低至4.8nM。传感机制研究表明，由于汞从MSA中“识别”，金纳米粒子形成聚集，并且汞与金（I）之间产生的强耦合相互作用进一步猝灭金纳米粒子的荧光，这协同导致对汞具有高度灵敏和选择性的荧光响应。该提出的策略还证明了用于水样中汞检测的可能性。