Rubio-Bueno P, Landete P, Ardanza B, Vázquez L, Soriano J B, Wix R, Capote A, Zamora E, Ancochea J, Naval-Gías L
University Hospital NISA Pardo de Aravaca, Madrid, Spain; Oral and Maxillofacial Department, Pneumology Department, Neurophysiology Department, Instituto de Investigación Hospital Universitario de la Princesa (IISP), Autónoma University, Madrid, Spain.
Oral and Maxillofacial Department, Pneumology Department, Neurophysiology Department, Instituto de Investigación Hospital Universitario de la Princesa (IISP), Autónoma University, Madrid, Spain.
Int J Oral Maxillofac Surg. 2017 Nov;46(11):1363-1371. doi: 10.1016/j.ijom.2017.07.003. Epub 2017 Jul 29.
Maxillomandibular advancement (MMA) can be effective for managing obstructive sleep apnoea (OSA); however, limited information is available on the predictor surgical variables. This study investigated whether normalization of the mandibular occlusal plane (MOP) was a determinant factor in curing OSA. Patients with moderate or severe OSA who underwent MMA were evaluated by preoperative and postoperative three-dimensional (3D) scans and polysomnograms. The postoperative value of MOP and the magnitude of skeletal advancement were the predictor variables; change in the apnoea-hypopnoea index (AHI) was the main outcome variable. Thirty-four subjects with a mean age of 41±14years and 58,8% female were analysed. The Epworth Sleepiness Scale (ESS) was 17.4±5.4 and AHI was 38.3±10.7 per hour before surgery. Postoperative AHI was 6.5±4.3 per hour (P<0.001) with 52.94% of the patients considered as cured, and 47.06% suffering from a mild residual OSA with ESS 0.8±1.4 (P<0.001). 3D changes revealed a volume increase of 106.3±38.8%. The mandible was advanced 10.4±3.9mm and maxilla 4.9±3.2mm. MOP postoperative value was concluded to be the best predictor variable. Treatment planning should include MOP normalization and a mandibular advancement between 6 and 10mm. The maxillary advancement would depend on the desired aesthetic changes and final occlusion.
上颌下颌前移术(MMA)可有效治疗阻塞性睡眠呼吸暂停(OSA);然而,关于预测手术效果的变量信息有限。本研究调查下颌咬合平面(MOP)的正常化是否是治愈OSA的决定性因素。对接受MMA治疗的中重度OSA患者进行术前和术后三维(3D)扫描及多导睡眠图评估。MOP的术后值和骨骼前移的幅度为预测变量;呼吸暂停低通气指数(AHI)的变化为主要结局变量。分析了34名平均年龄为41±14岁、女性占58.8%的受试者。术前Epworth嗜睡量表(ESS)为17.4±5.4,AHI为每小时38.3±10.7。术后AHI为每小时6.5±4.3(P<0.001),52.94%的患者被视为治愈,47.06%的患者患有轻度残余OSA,ESS为0.8±1.4(P<0.001)。三维变化显示体积增加了106.3±38.8%。下颌前移10.4±3.9mm,上颌前移4.9±3.2mm。MOP术后值被认为是最佳预测变量。治疗计划应包括MOP正常化和下颌前移6至10mm。上颌前移将取决于期望的美学变化和最终咬合情况。