Khare Anshika, Krishnappa Vinod, Kumar Deepak, Raina Rupesh
a Department of Internal Medicine , Northeast Ohio Medical University , Rootstown , OH , USA.
b Cleveland Clinic Akron General/Akron Nephrology Associates , Akron , OH , USA.
J Matern Fetal Neonatal Med. 2018 Nov;31(21):2923-2929. doi: 10.1080/14767058.2017.1358263. Epub 2017 Aug 2.
Neonatal renal cystic diseases have a great impact on the morbidity and mortality of the affected neonates and infants. A good insight into the pathophysiology, diagnosis and treatment options of various neonatal renal cystic diseases aid in early diagnosis and intervention, thereby preventing complications.
PubMed search was done for articles on "neonatal renal cystic diseases" and relevant publications including reviews were considered for our article.
Both hereditary and nonhereditary causes of cystic kidney diseases can result in severe morbidity and mortality. The main diagnostic modality is ultrasound imaging and most of the neonatal renal cystic diseases are detected during prenatal ultrasound screening. Commonly encountered neonatal renal cystic diseases are autosomal dominant polycystic kidney disease, autosomal recessive polycystic kidney disease and multicystic dysplastic kidney.
A thorough knowledge of various renal cystic diseases can be of extreme prognostic value. Physicians should be aware of the impact of early diagnosis and intervention on the lives of those affected. Further research about treatment of these diseases is ongoing and can result in breakthrough therapies for these patients.
新生儿肾囊性疾病对患病新生儿和婴儿的发病率和死亡率有很大影响。深入了解各种新生儿肾囊性疾病的病理生理学、诊断和治疗选择有助于早期诊断和干预，从而预防并发症。
在PubMed上搜索关于“新生儿肾囊性疾病”的文章，并考虑相关出版物，包括综述，用于撰写我们的文章。
囊性肾病的遗传和非遗传原因均可导致严重的发病率和死亡率。主要诊断方式是超声成像，大多数新生儿肾囊性疾病在产前超声筛查期间被检测到。常见的新生儿肾囊性疾病是常染色体显性多囊肾病、常染色体隐性多囊肾病和多囊性发育不良肾。
全面了解各种肾囊性疾病具有极高的预后价值。医生应意识到早期诊断和干预对患者生命的影响。关于这些疾病治疗的进一步研究正在进行中，可能会为这些患者带来突破性疗法。
