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资源有限环境下肠病性肢端皮炎的诊断

Diagnosis of acrodermatitis enteropathica in resource limited settings.

作者信息

Dev Tanvi, Sethuraman Gomathy

机构信息

Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

BMJ Case Rep. 2017 Aug 2;2017:bcr-2017-220928. doi: 10.1136/bcr-2017-220928.

Abstract

Acrodermatitis enteropathica (AE) is a rare inherited zinc deficiency that usually manifests in infancy within days in cases of bottlefed infants and days to weeks after weaning in breastfed infants. It is characterised by diarrhoea, dermatitis, alopecia and systemic symptoms. We report a case of acquired nutritional AE in a 6-month-old female infant who had diarrhoeal episodes and the characteristic dermatitis lesions in the acral and anogenital regions. She responded dramatically to oral zinc supplementation.

摘要

肠病性肢端皮炎(AE)是一种罕见的遗传性锌缺乏症,通常在人工喂养婴儿出生后数天内、母乳喂养婴儿断奶后数天至数周内于婴儿期发病。其特征为腹泻、皮炎、脱发和全身症状。我们报告一例6个月大女婴获得性营养性AE病例,该患儿有腹泻发作,且在手足和肛门生殖器区域有典型的皮炎病变。她对口服补充锌剂反应显著。

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