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青少年特发性关节炎滑膜炎症的超声成像

Ultrasound imaging of synovial inflammation in juvenile idiopathic arthritis.

作者信息

Chauvin Nancy A, Doria Andrea S

机构信息

Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA, 19104-4399, USA.

Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.

出版信息

Pediatr Radiol. 2017 Aug;47(9):1160-1170. doi: 10.1007/s00247-017-3934-6. Epub 2017 Aug 4.

Abstract

Juvenile idiopathic arthritis (JIA) is the most common rheumatic entity of childhood. The hallmark feature of all subtypes is joint inflammation. Imaging is used to evaluate the extent and severity of inflammation, degree of joint damage and response to treatment, which in turn impacts patient management. Ultrasound has become a useful adjunct to clinical examination because it shows promise in evaluating clinical and subclinical inflammation (synovitis, enthesitis) as well as cartilage and bone erosive changes. However more collaborative research is needed to help define the normal appearance of the growing skeleton, clarify the significance of subclinical findings and develop useful definitions, imaging protocols and scoring systems of disease.

摘要

幼年特发性关节炎(JIA)是儿童时期最常见的风湿性疾病。所有亚型的标志性特征是关节炎症。影像学用于评估炎症的程度和严重程度、关节损伤程度以及对治疗的反应,而这反过来又会影响患者的管理。超声已成为临床检查的有用辅助手段,因为它在评估临床和亚临床炎症(滑膜炎、附着点炎)以及软骨和骨侵蚀性改变方面显示出前景。然而,需要更多的合作研究来帮助确定生长中骨骼的正常表现,阐明亚临床发现的意义,并制定有用的疾病定义、成像方案和评分系统。

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