• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

皮肤搔抓障碍中症状严重程度的临床相关因素。

Clinical correlates of symptom severity in skin picking disorder.

作者信息

Grant Jon E, Chamberlain Samuel R

机构信息

Department of Psychiatry & Behavioral Neuroscience, University of Chicago, Chicago, IL, USA.

Department of Psychiatry, University of Cambridge, Cambridge and Peterborough NHS Foundation Trust (CPFT), UK.

出版信息

Compr Psychiatry. 2017 Oct;78:25-30. doi: 10.1016/j.comppsych.2017.07.001. Epub 2017 Jul 8.

DOI:10.1016/j.comppsych.2017.07.001
PMID:28779593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5584660/
Abstract

BACKGROUND

Skin picking disorder (SPD) remains poorly understood with limited data regarding its underlying pathophysiology and appropriate treatment choices. One approach to refining our treatment of SPD might be to better understand the range of illness severity and the clinical associations with severity.

METHODS

125 adults aged 18 to 65 with a primary, current DSM-5 diagnosis of SPD were assessed for the severity of their picking, using the Skin Picking Symptom Assessment Scale, and related mental health symptoms. To identify clinical and demographic measures associated with variation in disease severity, we utilized the statistical technique of partial least squares (PLS).

RESULTS

Greater SPD symptom severity was associated with higher Barratt attentional impulsiveness and motor impulsivity, higher Eysenck impulsivity, higher state anxiety/depression, having a current anxiety disorder, and having a lifetime substance use disorder.

CONCLUSIONS

The present analysis is, to our knowledge, the most complete assessment of clinical variables and their relationship to illness severity in a sample of adults with SPD. Aspects of impulsivity and anxiety are both strongly associated with worse illness severity, and functional disability, in SPD. Treatment approaches should incorporate these as possible treatment targets when developing new treatment approaches to this disorder.

摘要

背景

人们对皮肤搔抓障碍(SPD)的了解仍然有限,关于其潜在病理生理学和适当治疗选择的数据较少。优化我们对SPD治疗的一种方法可能是更好地了解疾病严重程度的范围以及与严重程度相关的临床关联。

方法

使用皮肤搔抓症状评估量表对125名年龄在18至65岁之间、目前主要诊断为DSM-5标准下SPD的成年人的搔抓严重程度及相关心理健康症状进行评估。为了确定与疾病严重程度变化相关的临床和人口统计学指标,我们采用了偏最小二乘法(PLS)统计技术。

结果

较高的SPD症状严重程度与较高的巴拉特注意冲动性和运动冲动性、较高的艾森克冲动性、较高的状态焦虑/抑郁、目前患有焦虑症以及有终生物质使用障碍有关。

结论

据我们所知,本分析是对患有SPD的成年人样本中临床变量及其与疾病严重程度关系的最全面评估。冲动性和焦虑方面均与SPD中更严重的疾病严重程度和功能残疾密切相关。在开发针对这种疾病的新治疗方法时,治疗方法应将这些作为可能的治疗靶点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cecd/5609656/be9c730b7021/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cecd/5609656/d4ce47574bab/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cecd/5609656/be9c730b7021/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cecd/5609656/d4ce47574bab/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cecd/5609656/be9c730b7021/gr2.jpg

相似文献

1
Clinical correlates of symptom severity in skin picking disorder.皮肤搔抓障碍中症状严重程度的临床相关因素。
Compr Psychiatry. 2017 Oct;78:25-30. doi: 10.1016/j.comppsych.2017.07.001. Epub 2017 Jul 8.
2
Impulsivity in body-focused repetitive behavior disorders: Disparate clinical associations between three distinct measures.身体聚焦重复行为障碍中的冲动性:三种不同测量方法之间的不同临床关联。
Int J Psychiatry Clin Pract. 2016;20(1):24-31. doi: 10.3109/13651501.2015.1102947. Epub 2015 Nov 6.
3
Skin picking disorder: Does a person's sex matter?皮肤搔抓障碍:性别有影响吗?
Ann Clin Psychiatry. 2022 Feb;34(1):15-20. doi: 10.12788/acp.0049.
4
Excoriation disorder: impulsivity and its clinical associations.搔抓障碍:冲动及其临床关联。
J Anxiety Disord. 2015 Mar;30:19-22. doi: 10.1016/j.janxdis.2014.12.010. Epub 2015 Jan 3.
5
Excoriation (skin-picking) disorder in adults: a cross-cultural survey of Israeli Jewish and Arab samples.成人搔抓障碍:对以色列犹太人和阿拉伯人样本的跨文化调查。
Compr Psychiatry. 2015 Apr;58:102-7. doi: 10.1016/j.comppsych.2014.12.008. Epub 2014 Dec 30.
6
Self-injurious skin picking: clinical characteristics and comorbidity.自我伤害性皮肤搔抓:临床特征与共病情况
J Clin Psychiatry. 1999 Jul;60(7):454-9. doi: 10.4088/jcp.v60n0707.
7
A structural MRI study of excoriation (skin-picking) disorder and its relationship to clinical severity.一项关于搔抓(皮肤搔抓)障碍及其与临床严重程度关系的结构 MRI 研究。
Psychiatry Res Neuroimaging. 2017 Nov 30;269:26-30. doi: 10.1016/j.pscychresns.2017.09.006. Epub 2017 Sep 8.
8
Statistical predictors of psychosocial impairment in body-focused repetitive behaviors.体部位重复行为所致心理社会功能损害的统计学预测因子。
CNS Spectr. 2022 Oct;27(5):621-625. doi: 10.1017/S1092852921000468. Epub 2021 Apr 30.
9
Skin picking disorder: prevalence, correlates, and associations with quality of life in a large sample.皮肤搔抓障碍:大样本中的流行率、相关性以及与生活质量的关系。
CNS Spectr. 2018 Oct;23(5):311-320. doi: 10.1017/S1092852918000871. Epub 2018 May 7.
10
Disorders of impulsivity in trichotillomania and skin picking disorder.拔毛癖和皮肤搔抓障碍中的冲动控制障碍。
J Psychiatr Res. 2024 Feb;170:42-46. doi: 10.1016/j.jpsychires.2023.12.011. Epub 2023 Dec 11.

引用本文的文献

1
Exploring skin picking disorder: aetiology, treatment, and future directions.探索皮肤搔抓障碍:病因、治疗及未来方向。
Postepy Dermatol Alergol. 2024 Dec;41(6):545-551. doi: 10.5114/ada.2024.142579. Epub 2024 Aug 9.
2
Prevalence and gender distribution of excoriation (skin-picking) disorder: A systematic review and meta-analysis.搔抓障碍(皮肤搔抓癖)的流行率和性别分布:系统评价和荟萃分析。
J Psychiatr Res. 2023 May;161:412-418. doi: 10.1016/j.jpsychires.2023.03.034. Epub 2023 Apr 1.
3
Clinical Characteristics of Youth with Trichotillomania (Hair-Pulling Disorder) and Excoriation (Skin-Picking) Disorder.

本文引用的文献

1
Skin picking in a non-clinical sample of young Polish adults. Prevalence and characteristics.波兰年轻成年人非临床样本中的皮肤搔抓行为。患病率及特征。
Compr Psychiatry. 2016 Nov;71:77-85. doi: 10.1016/j.comppsych.2016.08.013. Epub 2016 Aug 29.
2
N-Acetylcysteine in the Treatment of Excoriation Disorder: A Randomized Clinical Trial.N-乙酰半胱氨酸治疗搔抓障碍的随机临床试验。
JAMA Psychiatry. 2016 May 1;73(5):490-6. doi: 10.1001/jamapsychiatry.2016.0060.
3
Skin picking disorder.皮肤搔抓障碍。
拔毛癖(拔毛障碍)和皮肤搔抓障碍青少年的临床特征
Child Psychiatry Hum Dev. 2024 Aug;55(4):975-986. doi: 10.1007/s10578-022-01458-w. Epub 2022 Oct 31.
4
Pathological Skin Picking: Phenomenology and Associations With Emotions, Self-Esteem, Body Image, and Subjective Physical Well-Being.病理性皮肤搔抓:现象学及其与情绪、自尊、身体意象和主观身体健康的关联
Front Psychiatry. 2021 Oct 13;12:732717. doi: 10.3389/fpsyt.2021.732717. eCollection 2021.
5
Skin picking treatment with the Rothbaum cognitive behavioral therapy protocol: a randomized clinical trial.采用罗思鲍姆认知行为治疗方案治疗皮肤搔抓:一项随机临床试验。
Braz J Psychiatry. 2020 Sep-Oct;42(5):510-518. doi: 10.1590/1516-4446-2019-0636.
6
Improving skin picking diagnosis among Brazilians: validation of the Skin Picking Impact Scale and development of a photographic instrument.改善巴西人群中皮肤搔抓症的诊断:皮肤搔抓影响量表的验证及一种摄影工具的开发。
An Bras Dermatol. 2019 Sep-Oct;94(5):553-560. doi: 10.1016/j.abd.2018.10.001. Epub 2019 Sep 30.
7
A study on the correlates of habit-, reward-, and fear-related motivations in alcohol use disorder.一项关于酒精使用障碍中习惯、奖励和恐惧相关动机的相关性的研究。
CNS Spectr. 2019 Dec;24(6):597-604. doi: 10.1017/S1092852918001554.
Am J Psychiatry. 2012 Nov;169(11):1143-9. doi: 10.1176/appi.ajp.2012.12040508.
4
Skin picking disorder in university students: health correlates and gender differences.大学生皮肤搔抓障碍:健康相关性和性别差异。
Gen Hosp Psychiatry. 2013 Mar-Apr;35(2):168-73. doi: 10.1016/j.genhosppsych.2012.08.006. Epub 2012 Nov 2.
5
The Columbia-Suicide Severity Rating Scale: initial validity and internal consistency findings from three multisite studies with adolescents and adults.哥伦比亚自杀严重程度评定量表:三项包含青少年和成年人的多中心研究的初步有效性和内部一致性结果。
Am J Psychiatry. 2011 Dec;168(12):1266-77. doi: 10.1176/appi.ajp.2011.10111704.
6
A cognitive comparison of pathological skin picking and trichotillomania.病理性皮肤搔抓与拔毛癖的认知比较。
J Psychiatr Res. 2011 Dec;45(12):1634-8. doi: 10.1016/j.jpsychires.2011.07.012. Epub 2011 Aug 6.
7
The effects of brief cognitive-behaviour therapy for pathological skin picking: A randomized comparison to wait-list control.简短认知行为疗法对病理性皮肤搔抓的影响:与等待名单对照的随机比较。
Behav Res Ther. 2011 Jan;49(1):11-7. doi: 10.1016/j.brat.2010.09.005. Epub 2010 Sep 22.
8
The Skin Picking Impact Project: phenomenology, interference, and treatment utilization of pathological skin picking in a population-based sample.《皮肤搔抓影响项目:基于人群样本的病理性皮肤搔抓的现象学、干扰因素和治疗利用情况》
J Anxiety Disord. 2011 Jan;25(1):88-95. doi: 10.1016/j.janxdis.2010.08.007. Epub 2010 Aug 13.
9
A double-blind, placebo-controlled trial of lamotrigine for pathological skin picking: treatment efficacy and neurocognitive predictors of response.一项针对病理性皮肤搔抓的拉莫三嗪双盲、安慰剂对照试验:治疗效果和反应的神经认知预测因子。
J Clin Psychopharmacol. 2010 Aug;30(4):396-403. doi: 10.1097/JCP.0b013e3181e617a1.
10
Emotion regulation in pathological skin picking: findings from a non-treatment seeking sample.病理性皮肤搔抓的情绪调节:一项非治疗寻求者样本的研究结果。
J Behav Ther Exp Psychiatry. 2010 Sep;41(3):238-45. doi: 10.1016/j.jbtep.2010.01.009. Epub 2010 Feb 6.