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溢乳可能与从渗透泵型口服哌甲酯(MPH)转换为缓释型MPH有关:一例青少年病例

Galactorrhea Probably Related with Switching from Osmotic-release Oral System Methylphenidate (MPH) to Modified-release MPH: An Adolescent Case.

作者信息

Ekinci Ozalp, Gunes Serkan, Ekinci Nuran

机构信息

Department of Child and Adolescent Psychiatry, Mersin University School of Medicine, Mersin, Turkey.

出版信息

Clin Psychopharmacol Neurosci. 2017 Aug 31;15(3):282-284. doi: 10.9758/cpn.2017.15.3.282.

Abstract

Galactorrhea, as an adverse effect of psychotropic medications, usually develops due to high dose of antipsychotics. Selective serotonin reuptake inhibitors (SSRIs) have also been reported to be related to galactorrhea. To the best of our knowledge, no previous study reported galactorrhea with methylphenidate (MPH) use. Hereby, we report a case of an adolescent girl who developed galactorrhea after increasing his modifed-release oral MPH to 50 mg/day while under treatment of sertraline and very low dose haloperidol.

摘要

溢乳作为精神药物的一种不良反应,通常因高剂量抗精神病药物所致。据报道,选择性5-羟色胺再摄取抑制剂(SSRIs)也与溢乳有关。据我们所知,此前尚无使用哌甲酯(MPH)导致溢乳的研究报道。在此,我们报告一例青春期女孩病例,该女孩在接受舍曲林和极低剂量氟哌啶醇治疗期间,口服缓释MPH剂量增至50毫克/日之后出现了溢乳症状。

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