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HIV/AIDS患者的隐球菌抗原阴性脑膜脑炎

Cryptococcal antigen negative meningoencephalitis in HIV/AIDS.

作者信息

Chastain Daniel B, Guarner Jeannette, Franco-Paredes Carlos

机构信息

University of Georgia College of Pharmacy, 1000 Jefferson Street, Albany, GA, USA; Department of Pharmacy, Phoebe Putney Memorial Hospital, 417 3rd Avenue, Albany, GA, USA.

Division of Infectious Diseases, Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA.

出版信息

Diagn Microbiol Infect Dis. 2017 Oct;89(2):143-145. doi: 10.1016/j.diagmicrobio.2017.06.016. Epub 2017 Jul 3.

Abstract

Diagnosis of central nervous system cryptococcosis relies on a spectrum of methods but has improved with lateral flow diagnostic assays that detect capsular polysaccharide antigens of Cryptococcus. Here, we present the case of an HIV-infected African-American man with cryptococcal meningoencephalitis caused by a strain producing little or no capsule.

摘要

中枢神经系统隐球菌病的诊断依赖于一系列方法,但随着检测隐球菌荚膜多糖抗原的侧向流动诊断检测方法的出现,诊断情况有所改善。在此,我们报告一例感染人类免疫缺陷病毒(HIV)的非裔美国男性病例,其患有由产生极少或不产生荚膜的菌株引起的隐球菌性脑膜脑炎。

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