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具有稳态流的多高度装置中的液滴捕获和快速声释放。

Droplet trapping and fast acoustic release in a multi-height device with steady-state flow.

机构信息

Soft Matter and Biological Physics Group, Universität Augsburg, Universitätsstr. 1, D-86159 Augsburg, Germany.

出版信息

Lab Chip. 2017 Oct 11;17(20):3422-3430. doi: 10.1039/c7lc00378a.

Abstract

We demonstrate a novel multilayer polydimethylsiloxane (PDMS) device for selective storage and release of single emulsion droplets. Drops are captured in a microchannel cavity and can be released on-demand through a triggered surface acoustic wave pulse. The surface acoustic wave (SAW) is excited by a tapered interdigital transducer (TIDT) deposited on a piezoelectric lithium niobate (LiNbO) substrate and inverts the pressure difference across the cavity trap to push a drop out of the trap and back into the main flow channel. Droplet capture and release does not require a flow rate change, flow interruption, flow inversion or valve action and can be achieved in as fast as 20 ms. This allows both on-demand droplet capture for analysis and monitoring over arbitrary time scales, and continuous device operation with a high droplet rate of 620 drops per s. We hence decouple long-term droplet interrogation from other operations on the chip. This will ease integration with other microfluidic droplet operations and functional components.

摘要

我们展示了一种新颖的多层聚二甲基硅氧烷(PDMS)器件,用于选择性地存储和释放单乳液液滴。液滴被捕获在微通道腔室中,并可通过触发的表面声波脉冲按需释放。表面声波(SAW)由沉积在压电铌酸锂(LiNbO)衬底上的锥形叉指换能器(TIDT)激发,反转腔室陷阱两侧的压差,将液滴推出陷阱并返回主流道。液滴的捕获和释放不需要流速变化、流中断、流反转或阀门动作,最快可在 20 ms 内完成。这使得在任意时间尺度上对液滴进行按需捕获和分析成为可能,并以 620 个/秒的高液滴速率实现连续器件运行。因此,我们将长期的液滴检测与芯片上的其他操作解耦。这将便于与其他微流控液滴操作和功能组件集成。

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