Interventional Cardiology Unit, Cardio-Thoracic-Vascular Department, San Raffaele Scientific Institute, Milan, Italy.
Department of Cardiology, St. Antonius Hospital, Nieuwegein, the Netherlands.
JACC Cardiovasc Interv. 2017 Aug 14;10(15):1489-1497. doi: 10.1016/j.jcin.2017.06.002.
The aim of this study was to describe the procedural aspects and outcomes of retrograde chronic total occlusion (CTO) percutaneous coronary intervention (PCI) through ipsilateral collateral channels (ILCs).
Retrograde CTO PCI via ILCs is rarely performed, usually when no other retrograde options exist, and available evidence derives mostly from case reports.
A large retrospective multinational registry was compiled, including all consecutive patients undergoing retrograde CTO PCI through ILCs at 6 centers between September 2011 and October 2016. Success rates, as well as procedural complications and in-hospital outcomes, were studied.
A total of 126 patients (17% of all retrograde CTO PCIs) were included. The mean age was 65.7 ± 11.2 years, and the mean J-CTO (Multicenter CTO Registry in Japan) score was 2.36 ± 1.13. The target vessel was the circumflex coronary artery in 42%, the left anterior descending coronary artery in 39%, and the right coronary artery in 19%. The ILCs used were epicardial in 76% and septal in 24%. ILC anatomy was very heterogeneous. One guiding catheter was used in 80%, whereas the ping-pong technique was used in 20%. A retrograde wire could be advanced to the distal cap in 81%. Technical and procedural success rates were 87% and 82%, respectively. ILC perforation with need for intervention was observed in 5.6% and tamponade due to ILC perforation in 2.4%. One patient (0.8%) died.
Retrograde CTO PCI through ILCs is a challenging intervention that can be performed in difficult occlusions with high success rates and reasonable rates of complications by experienced operators.
本研究旨在描述通过同侧侧支循环(ILC)进行逆行慢性完全闭塞(CTO)经皮冠状动脉介入治疗(PCI)的手术过程和结果。
逆行 CTO PCI 通过 ILC 很少进行,通常是在没有其他逆行选择时进行,并且可用证据主要来自病例报告。
汇编了一项大型回顾性多中心注册研究,包括 2011 年 9 月至 2016 年 10 月在 6 个中心接受逆行 CTO PCI 通过 ILC 的所有连续患者。研究了成功率以及手术并发症和住院期间的结果。
共纳入 126 例患者(所有逆行 CTO PCI 的 17%)。平均年龄为 65.7 ± 11.2 岁,平均 J-CTO(日本多中心 CTO 注册研究)评分 2.36 ± 1.13。靶血管为回旋支 42%,前降支 39%,右冠状动脉 19%。使用的 ILC 为心外膜 76%,间隔 24%。ILC 解剖结构非常复杂。80%使用一个引导导管,20%使用乒乓技术。81%可将逆行导丝推进至远端闭塞。技术和程序成功率分别为 87%和 82%。观察到 5.6%的 ILC 穿孔需要介入治疗,2.4%的 ILC 穿孔引起填塞。1 例(0.8%)患者死亡。
由经验丰富的术者通过 ILC 进行逆行 CTO PCI 是一种具有挑战性的介入治疗方法,可在困难闭塞病变中进行,成功率高,并发症发生率合理。