Aryana Arash, d'Avila André, Cool Christina L, Miller Marc A, Garcia Fermin C, Supple Gregory E, Dukkipati Srinivas R, Lakkireddy Dhanunjaya, Bunch T Jared, Bowers Mark R, O'Neill Padraig Gearoid, Reddy Vivek Y, Marchlinski Francis E
Mercy General Hospital and Dignity Health Heart and Vascular Institute, Sacramento, CA, USA.
Instituto de Pesquisa em Arritmia Cardiaca, Hospital Cardiologico-Florianópolis, Florianópolis, Santa Catarina, Brazil.
J Cardiovasc Electrophysiol. 2017 Nov;28(11):1295-1302. doi: 10.1111/jce.13312. Epub 2017 Sep 1.
There is a paucity of data in favor of mechanical support during catheter ablation of ventricular tachycardia (VT). This study investigated the outcomes of VT ablation associated with mechanical support using percutaneous ventricular assist device (PVAD) versus intra-aortic balloon pump (IABP).
We retrospectively examined the outcomes of patients who underwent VT ablation associated with PVAD versus IABP from 2010 to 2013, captured by the Medicare Inpatient Standard Analytic File database. Data from 345 patients (PVAD = 230, IABP = 115) were examined. On admission, the incidence of heart failure was higher in PVAD (84.3% vs. 73.0%; P = 0.01) with similar rates of renal failure in PVAD versus IABP (33.0% vs. 37.4%; P = 0.42). However, PVAD was associated with reduced in-hospital cardiogenic shock (9.1% vs. 23.5%; P < 0.001), renal failure (11.7% vs. 21.7%; P = 0.01), and length of stay (8.4 ± 7.9 vs. 10.6 ± 7.5; P < 0.001), but with greater hospital discharges to home/self-care (66.0% vs. 51.6%; P = 0.02). Index mortality (6.5% vs. 19.1%; P = 0.001) and mortality in patients with cardiogenic shock (18.2% vs. 41.2%; P = 0.03) were significantly lower with PVAD versus IABP. Furthermore, PVAD was associated with lower all-cause (27.0% vs. 38.7%; P = 0.04) and heart failure-related (21.4% vs. 33.3%; P = 0.03) 30-day hospital readmissions, but with similar redo-VT ablation rates at 1 year (10.2% vs. 14.0%; P = 0.34).
Among the cases captured by the Medicare database, catheter ablation of VT associated with mechanical support using PVAD was associated with reduced in-hospital cardiogenic shock, renal failure, length of stay, hospital readmissions and mortality, but no difference in redo-VT ablation at 1 year.
在室性心动过速(VT)导管消融期间,支持使用机械辅助的相关数据较少。本研究调查了使用经皮心室辅助装置(PVAD)与主动脉内球囊反搏(IABP)进行机械支持的VT消融结果。
我们回顾性分析了医疗保险住院标准分析文件数据库中2010年至2013年接受PVAD或IABP相关VT消融患者的结果。对345例患者(PVAD组 = 230例,IABP组 = 115例)的数据进行了检查。入院时,PVAD组心力衰竭发生率较高(84.3% 对73.0%;P = 0.01),而PVAD组与IABP组肾衰竭发生率相似(33.0% 对37.4%;P = 0.42)。然而,PVAD与住院期间心源性休克减少相关(9.1% 对23.5%;P < 0.001)、肾衰竭减少相关(11.7% 对21.7%;P = 0.01)以及住院时间缩短相关(8.4 ± 7.9天对10.6 ± 7.5天;P < 0.001),但出院回家/自我护理的比例更高(66.0% 对51.6%;P = 0.02)。与IABP相比,PVAD组的指数死亡率(6.5% 对19.1%;P = 0.001)和心源性休克患者的死亡率(18.2% 对41.2%;P = 0.03)显著更低。此外,PVAD与30天内全因再入院率降低(27.0% 对38.7%;P = 0.04)和心力衰竭相关再入院率降低(21.4% 对33.3%;P = 0.03)相关,但1年时再次VT消融率相似(10.2% 对14.0%;P = 0.34)。
在医疗保险数据库记录的病例中,使用PVAD进行机械支持的VT导管消融与住院期间心源性休克、肾衰竭、住院时间、再入院率及死亡率降低相关,但1年时再次VT消融无差异。