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意大利北部癌症患者综合癌症姑息治疗计划的强度与临终急性医疗住院情况

Intensity of integrated cancer palliative care plans and end-of-life acute medical hospitalisation among cancer patient in Northern Italy.

作者信息

Pellizzari Michele, Rolfini Maria, Ferroni Eliana, Savioli Valentina, Gennaro Nicola, Schievano Elena, Avossa Francesco, Pinato Elisabetta, Ghiotto Maria Cristina, Figoli Franco, Mantoan Domenico, Brambilla Antonio, Fedeli Ugo, Saugo Mario

机构信息

Epidemiological Department of the Veneto Region, Padova, Italy.

Health and Social Care, Emilia Romagna Region, Italy.

出版信息

Eur J Cancer Care (Engl). 2018 Jan;27(1). doi: 10.1111/ecc.12742. Epub 2017 Aug 15.

Abstract

A high hospital utilisation at the end of life (EOL) is an indicator of suboptimal quality of health care. We evaluated the impact of the intensity of different Integrated Cancer Palliative Care (ICPC) plans on EOL acute medical hospitalisation among cancer decedents. Decedents of cancer aged 18-84 years, who were residents in two Italian regions, were investigated through integrated administrative data. Outcomes considered were prolonged hospital stay for medical reasons, 2+ hospitalisations during the last month of life and hospital death. The ICPC plans instituted 90 to 31 days before death represented the main exposure of interest. Other variables considered were gender, age class at death, marital status, recent hospitalisation and primary cancer site. Among 6,698 patients included in ICPC plans, 44.3% presented at least one critical outcome indicator; among these, 76.5% died in hospital, 60.3% had a prolonged (12+ days) medical hospitalisation, 19.1% had 2+ hospitalisations at the EOL. These outcomes showed a strong dose-response effect with the intensity of the ICPC plans, which is already evident at levels of moderate intensity. A well-ICPC approach can be very effective-beginning at low levels of intensity of care-in reducing the percentage of patients spending many days or dying in hospital.

摘要

临终时较高的医院利用率是医疗保健质量欠佳的一个指标。我们评估了不同综合癌症姑息治疗(ICPC)计划的强度对癌症死者临终时急性医疗住院的影响。通过综合行政数据对意大利两个地区18 - 84岁癌症死者进行了调查。所考虑的结果包括因医疗原因住院时间延长、生命最后一个月内2次及以上住院以及在医院死亡。在死亡前90至31天实施的ICPC计划是主要关注的暴露因素。其他考虑的变量包括性别、死亡时的年龄组、婚姻状况、近期住院情况和原发癌部位。在纳入ICPC计划的6698名患者中,44.3%至少出现一项关键结局指标;其中,76.5%在医院死亡,60.3%有延长(≥12天)的医疗住院时间,19.1%在临终时有2次及以上住院。这些结局与ICPC计划的强度呈现出强烈的剂量反应效应,在中等强度水平时就已明显。一种完善的ICPC方法在低护理强度水平时就能非常有效地降低患者长时间住院或在医院死亡的比例。

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