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孕期疫苗接种教育与婴儿免疫及时性

Vaccine Education During Pregnancy and Timeliness of Infant Immunization.

作者信息

Veerasingam Priya, Grant Cameron C, Chelimo Carol, Philipson Kathryn, Gilchrist Catherine A, Berry Sarah, Carr Polly Atatoa, Camargo Carlos A, Morton Susan

机构信息

General Paediatrics, Starship Children's Hospital, Auckland, New Zealand.

General Paediatrics, Starship Children's Hospital, Auckland, New Zealand;

出版信息

Pediatrics. 2017 Sep;140(3). doi: 10.1542/peds.2016-3727. Epub 2017 Aug 18.

Abstract

OBJECTIVES

Pregnant women routinely receive information in support of or opposing infant immunization. We aimed to describe immunization information sources of future mothers' and determine if receiving immunization information is associated with infant immunization timeliness.

METHODS

We analyzed data from a child cohort born 2009-2010 in New Zealand. Pregnant women ( = 6822) at a median gestation of 39 weeks described sources of information encouraging or discouraging infant immunization. Immunizations received by cohort infants were determined through linkage with the National Immunization Register ( = 6682 of 6853 [98%]). Independent associations of immunization information received with immunization timeliness were described by using adjusted odds ratios (ORs) and 95% confidence intervals (CIs).

RESULTS

Immunization information sources were described by 6182 of 6822 (91%) women. Of these, 2416 (39%) received information encouraging immunization, 846 (14%) received discouraging information, and 565 (9%) received both encouraging and discouraging information. Compared with infants of women who received no immunization information (71% immunized on-time), infants of women who received discouraging information only (57% immunized on time, OR = 0.49, 95% CI 0.38-0.64) or encouraging and discouraging information (61% immunized on time, OR = 0.51, 95% CI 0.42-0.63) were at decreased odds of receiving all immunizations on time. Receipt of encouraging information only was not associated with infant immunization timeliness (73% immunized on time, OR = 1.00, 95% CI 0.87-1.15).

CONCLUSIONS

Receipt, during pregnancy, of information against immunization was associated with delayed infant immunization regardless of receipt of information supporting immunization. In contrast, receipt of encouraging information is not associated with infant immunization timeliness.

摘要

目的

孕妇通常会收到支持或反对婴儿免疫接种的信息。我们旨在描述未来母亲的免疫接种信息来源,并确定接收免疫接种信息是否与婴儿免疫接种及时性相关。

方法

我们分析了2009 - 2010年在新西兰出生的儿童队列数据。孕周中位数为39周的孕妇(n = 6822)描述了鼓励或不鼓励婴儿免疫接种的信息来源。通过与国家免疫登记册联动确定队列婴儿接受的免疫接种情况(6853名中有6682名[98%])。使用调整后的优势比(OR)和95%置信区间(CI)描述所接收的免疫接种信息与免疫接种及时性的独立关联。

结果

6822名女性中有6182名(91%)描述了免疫接种信息来源。其中,2416名(39%)收到鼓励免疫接种的信息,846名(14%)收到不鼓励的信息,565名(9%)既收到鼓励又收到不鼓励的信息。与未收到免疫接种信息的女性的婴儿(71%按时接种)相比,仅收到不鼓励信息的女性的婴儿(57%按时接种,OR = 0.49,95% CI 0.38 - 0.64)或既收到鼓励又收到不鼓励信息的女性的婴儿(61%按时接种,OR = 0.51,95% CI 0.42 - 0.63)按时接种所有疫苗的几率降低。仅收到鼓励信息与婴儿免疫接种及时性无关(73%按时接种,OR = 1.00,95% CI 0.87 - 1.15)。

结论

孕期收到反对免疫接种的信息与婴儿免疫接种延迟相关,无论是否收到支持免疫接种的信息。相比之下,收到鼓励信息与婴儿免疫接种及时性无关。

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