2009 - 2013年佛兰德地区全科医疗中治疗淋病的抗生素处方：一项基于登记处的回顾性队列研究

Prescription of Antibiotics to Treat Gonorrhoea in General Practice in Flanders 2009-2013: A Registry-Based Retrospective Cohort Study.

作者信息

Schweikardt Christoph, Goderis Geert, Elli Steven, Coppieters Yves

机构信息

Université libre de Bruxelles (ULB), School of Public Health, Epidemiology, Biostatistics, and Clinical Research (Research Center 2) and Health Policies and Systems-International Health (Research Center 3), Campus Erasme, Bâtiment A, CP 594, route de Lennik 808, 1070 Brussels, Belgium.

Catholic University of Leuven, Academic Center for General Practice, Kapucijnenvoer 33, Blok J, Bus 7001, 3000 Leuven, Belgium.

出版信息

J Sex Transm Dis. 2017;2017:1860542. doi: 10.1155/2017/1860542. Epub 2017 Jul 31.

DOI:10.1155/2017/1860542

PMID:28831325

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5555009/

Abstract

BACKGROUND

General practitioners (GPs) as a group have been identified as playing an important role in gonorrhoea management in Flanders. Belgian guidelines recommended ceftriaxone or alternatively spectinomycin from 2008 onwards and azithromycin combination therapy since 2012.

OBJECTIVES

This study investigates to which extent contemporary gonorrhoea treatment guidelines were followed.

METHODS

A retrospective cohort study (2009-2013) of antibiotic prescriptions for gonorrhoea cases registered in the Flemish Intego general practice database was carried out. The database is based on electronic health record routine registration by over 90 GPs using the software programme Medidoc.

RESULTS

Ninety-one gonorrhoea cases with ten chlamydia and one genital trichomonas coinfections in 90 patients were registered between 2009 and 2013. The proportion of cases with ceftriaxone and/or spectinomycin prescriptions rose from 13% (two of 15 cases) in 2009 to 56% (nine of 16 cases) in 2013. Combination therapy of ceftriaxone and/or spectinomycin together with azithromycin rose from 0 of 15 cases (0%) in 2009 to 7 of 16 cases (44%) in 2013.

CONCLUSION

Although numbers are small, the results suggest that gonorrhoea therapy guideline adherence improved between 2009 and 2013.

摘要

背景

全科医生群体被认为在佛兰德地区淋病管理中发挥着重要作用。自2008年起，比利时指南推荐使用头孢曲松或大观霉素，自2012年起推荐使用阿奇霉素联合疗法。

目的

本研究调查了当代淋病治疗指南的遵循程度。

方法

对佛兰德综合医疗数据库中登记的淋病病例的抗生素处方进行了一项回顾性队列研究（2009 - 2013年）。该数据库基于90多名全科医生使用Medidoc软件程序进行的电子健康记录常规登记。

结果

2009年至2013年期间，共登记了91例淋病病例，90名患者中有10例合并衣原体感染，1例合并生殖器毛滴虫感染。使用头孢曲松和/或大观霉素处方的病例比例从2009年的13%（15例中的2例）升至2013年的56%（16例中的9例）。头孢曲松和/或大观霉素与阿奇霉素联合治疗从2009年15例中的0例（0%）升至2013年16例中的7例（44%）。