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经颅磁刺激治疗偏头痛的疗效:随机对照试验的荟萃分析

The efficacy of transcranial magnetic stimulation on migraine: a meta-analysis of randomized controlled trails.

作者信息

Lan Lihuan, Zhang Xiaoni, Li Xiangpen, Rong Xiaoming, Peng Ying

机构信息

Sun Yat-Sen University, Guangzhou, 510288, China.

Department of Neurology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Number 33, Yingfeng Road, Haizhu District, Guangzhou, 510288, China.

出版信息

J Headache Pain. 2017 Aug 22;18(1):86. doi: 10.1186/s10194-017-0792-4.

DOI:10.1186/s10194-017-0792-4
PMID:28831756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5567575/
Abstract

OBJECTIVES

As a non-invasive therapy, whether transcranial magnetic stimulation (TMS) is effective on migraine. This article was aimed to assess the efficacy of TMS on migraine based on randomized controlled trails (RCTs).

METHODS

We searched PubMed, Embase and Cochrane Library electronic databases for published studies which compared TMS group with sham group, conducted a meta-analysis of all RCTs.

RESULTS

Five studies, consisting of 313 migraine patients, were identified. Single-pulse transcranial magnetic stimulation is effective for the acute treatment of migraine with aura after the first attack (p = 0.02). And, the efficacy of TMS on chronic migraine was not significant (OR 2.93; 95% CI 0.71-12.15; p = 0.14).

CONCLUSIONS

TMS is effective for migraine based on the studies included in the article.

摘要

目的

作为一种非侵入性治疗方法,经颅磁刺激(TMS)对偏头痛是否有效。本文旨在基于随机对照试验(RCT)评估TMS对偏头痛的疗效。

方法

我们检索了PubMed、Embase和Cochrane图书馆电子数据库中比较TMS组与假刺激组的已发表研究,并对所有RCT进行了荟萃分析。

结果

共纳入5项研究,涉及313例偏头痛患者。单次经颅磁刺激对首次发作后有先兆的偏头痛急性治疗有效(p = 0.02)。而且,TMS对慢性偏头痛的疗效不显著(OR 2.93;95%CI 0.71 - 12.15;p = 0.14)。

结论

基于本文纳入的研究,TMS对偏头痛有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e3c/5567575/b06969529a57/10194_2017_792_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e3c/5567575/0db5da38df03/10194_2017_792_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e3c/5567575/036bfa5b3b55/10194_2017_792_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e3c/5567575/4e38d7b80106/10194_2017_792_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e3c/5567575/b06969529a57/10194_2017_792_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e3c/5567575/0db5da38df03/10194_2017_792_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e3c/5567575/036bfa5b3b55/10194_2017_792_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e3c/5567575/4e38d7b80106/10194_2017_792_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e3c/5567575/b06969529a57/10194_2017_792_Fig4_HTML.jpg

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Repetitive transcranial magnetic stimulation versus botulinum toxin injection in chronic migraine prophylaxis: a pilot randomized trial.重复经颅磁刺激与肉毒杆菌毒素注射用于慢性偏头痛预防的比较:一项初步随机试验
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