The First Affiliated Hospital of Jinan University, Guangzhou, China.
Department of Medical Ultrasound, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Sci Rep. 2017 Aug 25;7(1):9527. doi: 10.1038/s41598-017-10264-7.
Congenital Hypertrophic Pyloric Stenosis (CHPS) is a disease condition that is caused as a result of pylorus wall hypertrophy and hyperplasia. In this study, we used color Doppler flow imaging (CDFI) and Doppler artifacts technique to observe the blood flow of hypertrophic pylorus tissue and the dynamic imaging of liquid passing through the pyloric canal in CHPS infants. 65 cases of CHPS infants and 50 infants without CHPS served as control group. We found that there were statistically significant differences between the blood flow grade of muscular layer and mucosal layer between CHPS and control infants, but no significant differences were observed in the same group. Doppler artifacts technique demonstrated the whole process of contrast agent flow through pyloric canal was directly observed in 35 of 65 subjects, and the internal diameter of the pyloric canal was 1.93 ± 0.33mm.Conclusion that CDFI combined with color Doppler artifacts technique was proved to be effective to observe the distribution feature and blood flow grade in each layer of pyloric canal in CHPS patients. This method provides the evidence for judging the degree of pyloric stenosis clinically, and furnishes the basis of therapy along with its clinical significance and good application value.
先天性肥厚性幽门狭窄(CHPS)是一种由于幽门壁肥厚和增生引起的疾病。在本研究中,我们使用彩色多谱勒血流成像(CDFI)和多谱勒伪像技术观察肥厚性幽门组织的血流和 CHPS 婴儿通过幽门管的液体的动态成像。65 例 CHPS 婴儿和 50 例无 CHPS 的婴儿作为对照组。我们发现 CHPS 婴儿和对照组婴儿之间肌层和黏膜层的血流分级有统计学差异,但同一组之间没有显著差异。多普勒伪像技术显示,在 65 例受试者中,有 35 例直接观察到对比剂通过幽门管的全过程,幽门管的内径为 1.93±0.33mm。结论是 CDFI 结合彩色多普勒伪像技术被证明可以有效地观察 CHPS 患者幽门管各层的分布特征和血流分级。该方法为临床判断幽门狭窄程度提供了依据,为治疗提供了依据,具有重要的临床意义和良好的应用价值。