腔内和全身达托霉素治疗肺切除术后胸腔内感染的成功治疗。
Intracavitary and Systemic Daptomycin for Successful Treatment of a Postpneumonectomy Intrathoracic Infection.
机构信息
Department of Internal Medicine, Clínica Universidad de Navarra, Pamplona, Spain.
Division of Infectious Diseases, Clínica Universidad de Navarra, Pamplona, Spain.
出版信息
Antimicrob Agents Chemother. 2017 Oct 24;61(11). doi: 10.1128/AAC.01330-17. Print 2017 Nov.
Abstract
Treatment of an infected postpneumonectomy cavity is very difficult. We present a patient with an infection of a postpneumonectomy cavity by treated with local daptomycin for different dwell times, maintaining high antibiotic levels above the MIC. Clinical and microbiological cure were achieved successfully.
摘要
治疗肺切除术后感染性残腔非常困难。我们介绍了一例肺切除术后残腔感染的患者，采用局部达托霉素治疗不同的驻留时间，使抗生素浓度维持在高于 MIC 的水平。临床和微生物学治愈均获得成功。
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本文引用的文献
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Glucose Augments Killing Efficiency of Daptomycin Challenged Staphylococcus aureus Persisters.葡萄糖增强达托霉素对金黄色葡萄球菌持留菌的杀伤效率。
PLoS One. 2016 Mar 9;11(3):e0150907. doi: 10.1371/journal.pone.0150907. eCollection 2016.
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Daptomycin exposure and the probability of elevations in the creatine phosphokinase level: data from a randomized trial of patients with bacteremia and endocarditis.达托霉素暴露与肌酸磷酸激酶水平升高的概率：一项菌血症和心内膜炎患者随机试验的数据。
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Successful use of intraperitoneal daptomycin in the treatment of vancomycin-resistant enterococcus peritonitis.腹腔内使用达托霉素成功治疗耐万古霉素肠球菌腹膜炎。
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Daptomycin: a novel cyclic lipopeptide antimicrobial.达托霉素：一种新型环脂肽类抗菌药物。
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