Son Whee Sung, Shon Oog-Jin, Lee Dong-Chul, Park Sang-Jin, Yang Han Seok
Department of Orthopedic Surgery, Yeungnam University Medical Center, Daegu, Korea.
Department of Orthopedic Surgery, Bo Gang Hospital, Daegu, Korea.
Knee Surg Relat Res. 2017 Sep 1;29(3):172-179. doi: 10.5792/ksrr.16.040.
To assess the efficacy of open debridement and polyethylene exchange (ODPE) combined with proper antibiotic therapy in strictly selected patients with infection after total knee arthroplasty (TKA) and analyze factors associated with treatment failure.
From January 2010 to January 2014, 25 cases that underwent ODPE under the diagnosis of infection within four weeks after TKA or acute hematogenous infection within five days of symptom onset were reviewed in this study.
Treatment was successful in 22 out of 25 cases (88.0%). Factors associated with failure were accompanying infection (periprosthetic infection in the ipsilateral foot, cervical parotid abscess, and masticator space abscess) and diagnosis of rheumatoid arthritis (RA) before TKA. Resistant bacteria did not entail a risk. On clinical results, the mean postoperative Lysholm score and Korean Knee score were 81.4 and 79.4, respectively, the knee range of motion was 115.4°±12.9°, and duration of hospitalization was 32.3±8.4 days. On radiographic results, 3.47±1.56 mm joint line elevation and a valgus change of 0.61°±2.35° in knee alignment were observed.
ODPE combined with appropriate antibiotics therapy could be a useful treatment method for infection after TKA if the procedure is performed within a symptom duration of five days or less in the absence of accompanying infection in patients whose indication for TKA was not RA.
在经过严格挑选的全膝关节置换术(TKA)后感染患者中,评估开放性清创及聚乙烯垫片更换(ODPE)联合适当抗生素治疗的疗效,并分析与治疗失败相关的因素。
本研究回顾了2010年1月至2014年1月期间,25例在TKA后四周内诊断为感染或症状出现后五天内诊断为急性血源性感染并接受ODPE治疗的病例。
25例患者中有22例(88.0%)治疗成功。与治疗失败相关的因素包括合并感染(同侧足部假体周围感染、颈腮腺脓肿和咀嚼肌间隙脓肿)以及TKA术前诊断为类风湿关节炎(RA)。耐药菌并非危险因素。临床结果方面,术后平均Lysholm评分和韩国膝关节评分分别为81.4和79.4,膝关节活动范围为115.4°±12.9°,住院时间为32.3±8.4天。影像学结果显示,关节线抬高3.47±1.56 mm,膝关节对线外翻改变0.61°±2.35°。
对于TKA后感染,如果在症状出现五天或更短时间内进行该手术,且患者TKA的指征不是RA且无合并感染,ODPE联合适当的抗生素治疗可能是一种有效的治疗方法。