Department of Thoracic Surgery, GATA Haydarpasa Training Hospital, Istanbul, Turkey.
Department of Cardiology, GATA Haydarpasa Training Hospital, Istanbul, Turkey.
Indian J Med Res. 2017 Apr;145(4):498-502. doi: 10.4103/ijmr.IJMR_1133_14.
BACKGROUND & OBJECTIVES: Hyperhidrosis is a pathologic condition of excessive sweating in amounts greater than physiologic needs. Endoscopic thoracic sympathectomy (ETS) is a globally accepted treatment modality for primary palmar and axillary hyperhidrosis. ETS also has distinctive effects on the heart, circulatory and respiratory systems. In this study early effects of ETS on electrocardiographic (ECG) parameters of hyperhidrosis patients were evaluated.
Twelve-lead ECGs were performed on 72 patients who were free from cardiovascular, metabolic, neurological and pulmonary diseases and underwent planned ETS because of hyperhidrosis, before and after the procedure within the first 24 h. Heart rate (HR), PR, QT, corrected QT (QTc), QTc/Tpeak-Tend (TpTe) intervals, P-wave and QTc/TpTe dispersions were compared by ECG.
A total of 72 patients (24.1±6.0 yr, 17 female) were included in the study. The pre-operative HR of patients was significantly higher than post-operative HR of patients (73.8±12.8 vs. 68.1±12.6 beats/ min; P<0.001). The QTc dispersion (QTcd) durations of pre-operative patients were significantly longer than those of post-operative patients (51.5±6.3 vs. 44.9±5.6 msec; P<0.01). The TpTe dispersion value of pre-operative patients was significantly (P<0.001) higher than that of post-operative patients.
INTERPRETATION & CONCLUSIONS: Our study showed that ETS through clipping procedure had positive effects on the mechanisms of arrhythmia by reducing HR, QTcd, TpTe and TpTe dispersion parameters of ECG in early periods in hyperhidrosis patients.
多汗症是一种病理性出汗过多的病症，超过了生理需求。胸腔镜胸交感神经切除术（ETS）是一种全球公认的原发性手掌和腋窝多汗症的治疗方法。ETS 对心脏、循环和呼吸系统也有独特的影响。在这项研究中，评估了 ETS 对多汗症患者心电图（ECG）参数的早期影响。
对 72 例无心血管、代谢、神经和肺部疾病的患者进行了 12 导联心电图检查，这些患者因多汗症计划接受 ETS，并在术后 24 小时内进行了心电图检查。比较了心率（HR）、PR、QT、校正 QT（QTc）、QTc/Tpeak-Tend（TpTe）间期、P 波和 QTc/TpTe 离散度。
共纳入 72 例患者（24.1±6.0 岁，17 例女性）。患者术前 HR 明显高于术后 HR（73.8±12.8 与 68.1±12.6 次/分；P<0.001）。术前患者的 QTcd 持续时间明显长于术后患者（51.5±6.3 与 44.9±5.6 msec；P<0.01）。术前患者的 TpTe 离散值明显高于术后患者（P<0.001）。
我们的研究表明，通过夹闭术式的 ETS 在早期对多汗症患者的心电图机制产生了积极影响，降低了 HR、QTcd、TpTe 和 TpTe 离散参数。
