Prata Joana, Martins Amadeu Quelhas, Ramos Sónia, Rocha-Gonçalves Francisco, Coelho Rui
Cardiovascular Research Unit. Faculty of Medicine. University of Porto. Porto. Portugal.
Department of Psychology. Universidade Europeia. Laureate International Universities. Lisbon. Portugal. Microenvironments for New Therapies Group. Instituto de Investigação e Inovação em Saúde. University of Porto. Porto. Portugal.
Acta Med Port. 2017 May 31;30(5):373-380. doi: 10.20344/amp.7871.
The outcomes of cardiovascular disease are consistently worse among women, regardless of age or disease severity. Such trend might arise from psychosocial factors, which should be examined in this population. Obective: To evaluate the influence of type-D personality on anxiety and depression symptoms reported by female patients after a first acute coronary syndrome.
As part of a larger study, 34 female patients with a first acute coronary syndrome were compared with 43 controls on psychosocial measures (Hospital Anxiety and Depression Scale; type-D personality, DS - 14).
Hypertension (p < 0.001), diabetes (p < 0.05), dyslipidemia (p < 0.05), type-D personality (p = 0.001) and anxiety (p < 0.001) were more prevalent among patients. Exercise (p < 0.05) and antidepressant use (p < 0.05) were more common among controls. Logistic regression analysis confirmed that higher prevalence of hypertension (p < 0.05), dyslipidemia (p < 0.05), type-D personality (p < 0.05), anxiety (p < 0.05) and less antidepressant use (p < 0.05), were independently associated with acute coronary syndrome. Type-D personality was associated with higher Hospital Anxiety and Depression Scale scores in controls (anxiety: p = 0.001; depression: p < 0.001) but not in patients.
High anxiety after an acute coronary syndrome might reflect a short-term adaptive response, albeit worsening the disease long-term prognosis. The lack of differences in some group comparisons (patients versus controls for depression scores; type-D 'positive' versus type-D 'negative' for anxiety and depression scores within patients) is discussed.
Type-D personality, high anxiety, hypertension and dyslipidemia seem to cluster among female acute coronary syndrome patients. Nevertheless, type-D personality itself was not associated with higher anxiety and depressive scores during the post-acute period.
无论年龄或疾病严重程度如何,女性心血管疾病的预后始终较差。这种趋势可能源于心理社会因素,应对这一人群进行研究。目的:评估D型人格对首次急性冠状动脉综合征后女性患者报告的焦虑和抑郁症状的影响。
作为一项更大规模研究的一部分,对34例首次发生急性冠状动脉综合征的女性患者与43例对照者进行了心理社会指标(医院焦虑抑郁量表;D型人格,DS-14)的比较。
患者中高血压(p<0.001)、糖尿病(p<0.05)、血脂异常(p<0.05)、D型人格(p=0.001)和焦虑(p<0.001)更为普遍。运动(p<0.05)和使用抗抑郁药(p<0.05)在对照者中更为常见。逻辑回归分析证实,高血压(p<0.05)、血脂异常(p<0.05)、D型人格(p<0.05)、焦虑(p<0.05)的较高患病率以及较少使用抗抑郁药(p<0.05)与急性冠状动脉综合征独立相关。D型人格与对照者较高的医院焦虑抑郁量表评分相关(焦虑:p=0.001;抑郁:p<0.001),但与患者无关。
急性冠状动脉综合征后的高度焦虑可能反映了一种短期适应性反应,尽管会恶化疾病长期预后。讨论了一些组间比较缺乏差异的情况(患者与对照者的抑郁评分;患者中D型“阳性”与D型“阴性”的焦虑和抑郁评分)。
D型人格,高度焦虑、高血压和血脂异常似乎在女性急性冠状动脉综合征患者中聚集。然而,D型人格本身在急性期后与较高的焦虑和抑郁评分无关。