PHACE综合征的产前危险因素：一项使用PHACE综合征国际临床登记处和基因库的研究
Prenatal Risk Factors for PHACE Syndrome: A Study Using the PHACE Syndrome International Clinical Registry and Genetic Repository.
作者信息
Wan Joy, Steiner Jack, Baselga Eulalia, Blei Francine, Cordisco Maria, Garzon Maria C, Goddard Deborah S, Haggstrom Anita, Krol Alfons, Frieden Ilona J, Metry Denise, Morel Kimberly D, Verhagen Judith M A, Wargon Orli, Drolet Beth A, Siegel Dawn H
机构信息
Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA.
Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI.
出版信息
J Pediatr. 2017 Nov;190:275-279. doi: 10.1016/j.jpeds.2017.06.055. Epub 2017 Sep 1.
Abstract
The cause of PHACE syndrome is unknown. In a study of 218 patients, we examined potential prenatal risk factors for PHACE syndrome. Rates of pre-eclampsia and placenta previa in affected individuals were significantly greater than in the general population. No significant risk factor differences were detected between male and female subjects.
摘要
PHACE综合征的病因尚不清楚。在一项对218名患者的研究中，我们检查了PHACE综合征潜在的产前风险因素。受影响个体中先兆子痫和前置胎盘的发生率显著高于一般人群。未检测到男性和女性受试者之间存在显著的风险因素差异。
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本文引用的文献
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Evaluation of maternal history of miscarriage, infertility and in vitro fertilization as associated factors in PHACE.
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