Zhao Ying, Shi Chen, Huang Pu
Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Zhongguo Zhong Yao Za Zhi. 2016 Feb;41(4):743-747. doi: 10.4268/cjcmm20160434.
To assess the clinical use and occurrence of adverse reactions of Xiyanping injection, and to provide reference for rational drug use in the clinic. Based on hospital central monitoring method, the clinical data of Xiyanping injection in our hospital in 2014 was tracked and analyzed. A total of 848 inpatients were enrolled in this study. Among them, 39.9% were not in accordance with the medication purpose. In practice, the dose more than the limits prescribed by the instructions of child and adult were accounted for 1.72% and 6.62%, respectively; improper choice of solvent, accounting for 3.18%; both the choice of versus intravenous drip and aerosol inhalati administration route were reasonable; mixed with other drug, accounting for 2.24%. The incidence of ADR of Xiyanping injection was 0.12%, which showed good safety. Irrational use of Xiyanping injection existed in clinics, and the use should be strengthened and regulated. The manufacturer should improve the drug instruction of usage and dosage.
评价喜炎平注射液的临床使用情况及不良反应发生情况,为临床合理用药提供参考。采用医院集中监测方法,对我院2014年喜炎平注射液的临床资料进行跟踪分析。本研究共纳入848例住院患者。其中,39.9%的用药目的不明确。实际应用中,儿童和成人剂量超过说明书规定限量的分别占1.72%和6.62%;溶媒选择不当占3.18%;静脉滴注与雾化吸入两种给药途径选择均合理;与其他药物联用占2.24%。喜炎平注射液不良反应发生率为0.12%,安全性良好。临床存在喜炎平注射液不合理使用现象,应加强使用管理与规范。药品生产企业应完善药品用法用量说明书。