[结节性淋巴细胞为主型霍奇金淋巴瘤：LP细胞在双特异性磷酸酶2、血清/糖皮质激素调节激酶1和JunB中显示出复发性突变] - Suppr

[Nodular lymphocyte-dominant Hodgkin's lymphoma : LP cells show recurrent mutations in DUSP2, SGK1 and JUNB].

作者信息

Hartmann S

机构信息

Dr. Senckenbergisches Institut für Pathologie, Universitätsklinikum Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland.

出版信息

Pathologe. 2017 Nov;38(Suppl 2):154-157. doi: 10.1007/s00292-017-0335-4.

DOI:10.1007/s00292-017-0335-4

PMID:28879465

Abstract

摘要

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[Nodular lymphocyte-dominant Hodgkin's lymphoma : LP cells show recurrent mutations in DUSP2, SGK1 and JUNB].

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Hodgkin's disease, lymphocyte predominance type, nodular--further evidence for a B cell derivation. L & H variants of Reed-Sternberg cells express L26, a pan B cell marker.

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本文引用的文献

Characterization and Purification of Neoplastic Cells of Nodular Lymphocyte Predominant Hodgkin Lymphoma from Lymph Nodes by Flow Cytometry and Flow Cytometric Cell Sorting.

Am J Pathol. 2017 Feb;187(2):304-317. doi: 10.1016/j.ajpath.2016.10.007. Epub 2016 Dec 18.

Highly recurrent mutations of SGK1, DUSP2 and JUNB in nodular lymphocyte predominant Hodgkin lymphoma.

Leukemia. 2016 Apr;30(4):844-53. doi: 10.1038/leu.2015.328. Epub 2015 Dec 10.

Long-Term Course of Patients With Stage IA Nodular Lymphocyte-Predominant Hodgkin Lymphoma: A Report From the German Hodgkin Study Group.

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[Nodular lymphocyte-dominant Hodgkin's lymphoma : LP cells show recurrent mutations in DUSP2, SGK1 and JUNB].

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