蛇咬伤所致血栓性微血管病导致肾皮质坏死。
Snakebite Induced Thrombotic Microangiopathy Leading to Renal Cortical Necrosis.
作者信息
Gn Ying Mao, Ponnusamy Arvind, Thimma Vikram
机构信息
Renal Department, Royal Preston Hospital, Preston, UK.
Renal Department, Velammal Medical College Hospital, Madurai, India.
出版信息
Case Rep Nephrol. 2017;2017:1348749. doi: 10.1155/2017/1348749. Epub 2017 Aug 13.
Renal complications from snakebite result in high mortality and morbidity. Acute kidney injury (AKI) occurs in 5-30% of cases. Renal manifestation could include acute tubular necrosis, cortical necrosis, interstitial nephritis, glomerulonephritis, and vasculitis. We present a case of thrombotic microangiopathy (TMA) resulting in renal cortical necrosis. Renal biopsy showed fibrin thrombi in glomeruli and arterioles with cortical necrosis. Our patient progressed to end-stage renal disease.
蛇咬伤引起的肾脏并发症会导致高死亡率和高发病率。5%至30%的病例会发生急性肾损伤（AKI）。肾脏表现可能包括急性肾小管坏死、皮质坏死、间质性肾炎、肾小球肾炎和血管炎。我们报告一例导致肾皮质坏死的血栓性微血管病（TMA）病例。肾活检显示肾小球和小动脉中有纤维蛋白血栓，并伴有皮质坏死。我们的患者进展为终末期肾病。
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