Tana Marco, Tana Claudio, Schiavone Cosima, Verdiani Valerio, Palermo Carlo, Alessandri Massimo, Giamberardino Maria Adele, Montagnani Andrea
a Internal Medicine Unit , Grosseto , Italy.
b Internal Medicine and Critical Subacute Care Unit, Medicine Geriatric-Rehabilitation Department , University-Hospital of Parma , Parma , Italy.
Hosp Pract (1995). 2017 Dec;45(5):258-264. doi: 10.1080/21548331.2017.1378059. Epub 2017 Sep 15.
The spontaneous isolated celiac artery dissection (siCAD) represents a challenging cause of abdominal pain and complete information regarding incidence, etiology and risk factors in the young is still lacking. In this study, we report a case of siCAD occurred in a young woman and we systematically searched for information on siCADs in literature databases.
PubMed/Embase and Cochrane were searched for, using the following terms: Isolated celiac trunk dissection, isolated celiac artery dissection, celiac artery dissection, celiac trunk dissection, spontaneous isolated visceral artery dissection, spontaneous isolated dissection of visceral arteries, isolated celiac artery dissection in the young, isolated celiac trunk dissection in the young. Patients were included if they were younger than 50 years, if they had a spontaneous etiology and a selective involvement of the celiac artery (with or without involvement of its branches).
180 studies were found, and 18 remained after screening. Twenty-one patients (male = 19, female = 2) with siCADs were included. Mean age was 44.71 ± 3.61 years. Hypertension was the most prevalent comorbidity. All patients presented with abdominal pain, more often located in the epigastrium (n = 11). Almost all patients underwent CT to confirm the diagnosis. A conservative treatment was adopted in 13 patients while an invasive approach was adopted in 8 patients (endovascular approach in 7).
siCADs represent a rare but important cause of vascular dissection in the young. Uncomplicated cases can be safely treated with conservative strategies. The surgical or endovascular repair is indicated when dissections complicate or symptoms persist despite an adequate conservative treatment.
自发性孤立性腹腔干动脉夹层(siCAD)是腹痛的一个具有挑战性的病因,目前仍缺乏关于年轻人发病率、病因和危险因素的完整信息。在本研究中,我们报告了一例发生在年轻女性身上的siCAD病例,并系统地在文献数据库中搜索了有关siCAD的信息。
在PubMed/Embase和Cochrane数据库中进行检索,使用以下检索词:孤立性腹腔干夹层、孤立性腹腔动脉夹层、腹腔动脉夹层、腹腔干夹层、自发性孤立性内脏动脉夹层、自发性孤立性内脏动脉夹层、年轻人中的孤立性腹腔动脉夹层、年轻人中的孤立性腹腔干夹层。纳入标准为年龄小于50岁、病因自发且腹腔动脉选择性受累(无论其分支是否受累)的患者。
共检索到180项研究,筛选后剩余18项。纳入了21例siCAD患者(男性19例,女性2例)。平均年龄为44.71±3.61岁。高血压是最常见的合并症。所有患者均出现腹痛,最常见于上腹部(n = 11)。几乎所有患者都接受了CT检查以确诊。13例患者采用保守治疗,8例患者采用侵入性治疗方法(7例采用血管内治疗方法)。
siCAD是年轻人血管夹层的一种罕见但重要的病因。无并发症的病例可采用保守策略安全治疗。当夹层出现并发症或在充分的保守治疗后症状仍持续时,建议进行手术或血管内修复。